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EMU012551

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Cftr

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20 μG
$220.00
50 μG
$391.00

$220.00

Usually ships in 3 weeks (4 to 6 weeks for custom orders).
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20 μG
$220.00
50 μG
$391.00

About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

$220.00

Usually ships in 3 weeks (4 to 6 weeks for custom orders).

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GTCGTCTCGGCATTACAACCCTACATCTTCCTAGCAACGGTGCCAGGGCTAGTAGTCTTTATTTTACTGAGGGCCTACTTCCTTCATACAGCACAGCAGCTCAAACAACTGGAATCTGAAGGCAGGAGTCCAATTTTCACCCACCTTGTGACAAGCTTAAAAGGACTCTGGACACTTCGAGCCTTCCGACGCCAGACTTACTTTGAAACTCTGTTCCACAAAGCTCTGAATTTGCACACTGCCAACTGGTTTATGTATCTGGCAACCTTGCGCTGGTTCCAAATGAGAATAGACATGATATTTGTCCTCTTCTTCATTGTTGTTACCTTCATCTCCATTTTAACAACAGGTGAAGGAGAAGGAACAGCTGGTATTATTCTAACTTTAGCTATGAATATCATGAGTACTTTGCAGTGGGCTGTGA

Ensembl | mouse accession no.

ENSMUSG00000041301

NCBI accession no.

NM_021050

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... CFTR(12638) , Cftr(12638)

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product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

Ensembl | mouse accession no.

ENSMUSG00000041301

Ensembl | mouse accession no.

ENSMUSG00000028039

Ensembl | mouse accession no.

-

Ensembl | mouse accession no.

ENSMUSG00000027997

Gene Information

mouse ... CFTR(12638), Cftr(12638)

Gene Information

mouse ... EFNA3(13638), Efna3(13638)

Gene Information

human ... CNR1(1268), CNR1(1268)

Gene Information

mouse ... CASP6(12368), Casp6(12368)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

NCBI accession no.

NM_021050

NCBI accession no.

NM_010108

NCBI accession no.

NM_033181

NCBI accession no.

NM_009811

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Ye Chun Ruan et al.
Journal of cell science, 127(Pt 20), 4396-4408 (2014-08-12)
Mutations in CFTR lead to dysfunction of tubular organs, which is currently attributed to impairment of its conductive properties. We now show that CFTR regulates tight junction assembly and epithelial cell differentiation through modulation of the ZO-1-ZONAB pathway. CFTR colocalizes

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