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EHU065181

Sigma-Aldrich

MISSION® esiRNA

targeting human FKBP10

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCTCTGCCGTGCTAATCTTCAACGTCCATGTCATTGACTTCCACAACCCTGCGGATGTGGTGGAAATCAGGACACTGTCCCGGCCATCTGAGACCTGCAATGAGACCACCAAGCTTGGGGACTTTGTTCGATACCATTACAACTGTTCTTTGCTGGACGGCACCCAGCTGTTCACCTCGCATGACTACGGGGCCCCCCAGGAGGCGACTCTCGGGGCCAACAAGGTGATCGAAGGCCTGGACACGGGCCTGCAGGGCATGTGTGTGGGAGAGAGGCGGCAGCTCATCGTGCCCCCGCACCTGGCCCACGGGGAGAGTGGAGCCCGGGGAGTCCCAGGCAGTGCTGTGCTGCTGTTTGAGGTGGAGCTGGTGTCCCGGGAGGATGGGCTGCCCACAGGCTACCTGTTTGTGTGGCACAAGGACCCTCCTGCCAACCTGTTTGAAGACATGGACCTCAACAAGGATGG

Ensembl | human accession no.

ENSG00000141756

NCBI accession no.

NM_021939

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... FKBP10(60681) , FKBP10(60681)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Larissa Knüppel et al.
Respiratory research, 19(1), 67-67 (2018-04-21)
In idiopathic pulmonary fibrosis (IPF), fibroblasts gain a more migratory phenotype and excessively secrete extracellular matrix (ECM), ultimately leading to alveolar scarring and progressive dyspnea. Here, we analyzed the effects of deficiency of FK506-binding protein 10 (FKBP10), a potential IPF
Giorgio Ramadori et al.
Cell reports, 30(11), 3851-3863 (2020-03-19)
Cancer therapy is limited, in part, by lack of specificity. Thus, identifying molecules that are selectively expressed by, and relevant for, cancer cells is of paramount medical importance. Here, we show that peptidyl-prolyl-cis-trans-isomerase (PPIase) FK506-binding protein 10 (FKBP10)-positive cells are

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