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EHU026711

Sigma-Aldrich

MISSION® esiRNA

targeting human CEP192

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TATTTGTGCAGCCATTTGGACCTCAGTATGAGGTAGTGTTAAAAGGCGAAGTCATTTCTTCAGGAAGTAAACCTCTGTCACCTGGACCTTGCTTAGATATTCCATCGATTTTGTCCAACAAACAATTTCTGGCTTGGGGAGGAGTCCCTCTAGGTAGAACACAGCTTCAGAAACTAGCTTTAAGAAATAATTCTGCATCTACAACTCAACATTTACGACTGCTTATTAGAGGACAAGATCAGGACTGCTTTCAGCTTCAGAACACTTTTGGTTCAGAACAGCGATTGACCAGTAACTGTGAGATCAGAATTCACCCAAAGGAAGACATTTTCATCTCTGTATTATTTGCACCTACTCGATTATCTTGCATGTTGGCTAGACTAGAAATCAAACAACTTGGAAATCGATCACAACCAGG

Ensembl | human accession no.

ENSG00000101639

NCBI accession no.

NM_032142

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... CEP192(55125) , CEP192(55125)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Franz Meitinger et al.
Nature, 585(7825), 440-446 (2020-09-11)
Centrosomes catalyse the formation of microtubules needed to assemble the mitotic spindle apparatus1. Centrosomes themselves duplicate once per cell cycle, in a process that is controlled by the serine/threonine protein kinase PLK4 (refs. 2,3). When PLK4 is chemically inhibited, cell
Wangfei Chi et al.
The Journal of cell biology, 220(1) (2020-12-23)
Centrosome duplication occurs under strict spatiotemporal regulation once per cell cycle, and it begins with cartwheel assembly and daughter centriole biogenesis at the lateral sites of the mother centrioles. However, although much of this process is understood, how centrosome duplication

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