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E1279

Enoximone

solid

Synonym(s):

1,3-Dihydro-4-methyl-5-(4-methylthiobenzoyl)-2H-imidazol-2-one

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Pack SizeSKUAvailabilityPrice
10 mg

Available to ship TODAYfromMILWAUKEE

$253.00
$215.05

About This Item

Empirical Formula (Hill Notation):
C12H12N2O2S
CAS Number:
77671-31-9
Molecular Weight:
248.30
NACRES:
NA.77
PubChem Substance ID:
24278408
UNSPSC Code:
41106305
MDL number:
MFCD00867130
Form:
solid

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form

solid

Quality Segment

100

color

light yellow

solubility

DMSO: soluble 28 mg/mL

SMILES string

CSc1ccc(cc1)C(=O)C2=C(C)NC(=O)N2

InChI

1S/C12H12N2O2S/c1-7-10(14-12(16)13-7)11(15)8-3-5-9(17-2)6-4-8/h3-6H,1-2H3,(H2,13,14,16)

InChI key

ZJKNESGOIKRXQY-UHFFFAOYSA-N

Gene Information

human ... PDE3A(5139), PDE3B(5140)

Biochem/physiol Actions

Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE. Increased cAMP results in enhanced contractility of the heart.
Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
D9190S5321O9387
Enoximone solid

Sigma-Aldrich

E1279

Enoximone

DCEBIO ≥98% (HPLC), solid

Sigma-Aldrich

D9190

DCEBIO

S15535 ≥98% (HPLC), solid

Sigma-Aldrich

S5321

S15535

Oxatomide ≥99%

Sigma-Aldrich

O9387

Oxatomide

form

solid

form

solid

form

solid

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

DMSO: soluble 28 mg/mL

solubility

DMSO: >10 mg/mL

solubility

DMSO: ~6 mg/mL, H2O: insoluble

solubility

DMSO: soluble, ethanol: soluble

color

light yellow

color

white to off-white

color

white

color

white

Gene Information

human ... PDE3A(5139), PDE3B(5140)

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

Gene Information

-

Gene Information

human ... DRD3(1814)

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000239177
0000239177
0000177485
0000177485
0000100763

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Articles

Discover Bioactive Molecules for Nucleotides

Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.

Global Trade Item Number

SKUGTIN
E1279-10MG04061833629697
E1279-50MG04061833629703

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