E0278

Ephrin-A3/Fc Chimera human

>90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

• Synonym(s): EFL-2, Ehk1-L, LERK-3
• MDL number: MFCD01867032
• UNSPSC Code: 51111800
• NACRES: NA.32

Properties

• biological source: human
• Quality Level: 200
• recombinant: expressed in NSO cells
• assay: >90% (SDS-PAGE)
• form: lyophilized powder
• mol wt: monomer calculated mol wt 47.7 kDa; ~90 kDa by SDS-PAGE (reducing)
• packaging: pkg of 200 μg
• storage condition: avoid repeated freeze/thaw cycles
• impurities: endotoxin, tested
• UniProt accession no.: P52797
• Storage temp.: −20°C
• Gene Information: human ... EFNA3(1944)

Description

Biochem/physiol Actions

Member of the ephrin ligand family that binds Eph receptor tyrosine kinases (EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, and EphB1). Involved in pattern formation and morphogenesis.

Other Notes

Extracellular domain of human ephrin-A3 (amino acids 1-209) is fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Analysis Note

The biological activity is measured by its ability to bind immobilized recombinant mouse EphA6/Fc in ELISA.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)