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Key Documents

D3875

Sigma-Aldrich

Sodium dehydrocholate

~95%

Synonym(s):

3,7,12-Trioxo-5β-cholanic acid sodium salt, Dehydrocholic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C24H33NaO5
CAS Number:
Molecular Weight:
424.51
Beilstein/REAXYS Number:
4119624
EC Number:
MDL number:
UNSPSC Code:
12000000

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description

anionic

assay

~95%

SMILES string

[Na+].[H][C@@]12CC(=O)CC[C@]1(C)[C@@]3([H])CC(=O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])C(=O)C2)[C@H](C)CCC([O-])=O

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Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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    M K Mohanty et al.
    Tropical gastroenterology : official journal of the Digestive Diseases Foundation, 31(3), 184-189 (2011-05-13)
    Small ductules communicating with the bile ducts have been described at the porta hepatis in extrahepatic biliary atresia (EHBA) and these form the basis for hepatic portoenterostomy. The use of cholagogues like dehydrocholic acid (DHC) and ursodeoxycholic acid (UDCA) to
    Tao Huang et al.
    Biotechnology and applied biochemistry, 42(Pt 1), 47-56 (2004-12-23)
    A novel chemically modified insulin, -NB29-DHC-insulin (where DHC-insulin stands for dehydrocholyl-insulin), was prepared by covalent linkage of DHC (dehydrocholic acid) to the -amino group of LysB29 without any protecting agent and analysed by PAGE and reversed-phase HPLC. DHC-insulin was identified
    Ana I Prieto et al.
    Journal of bacteriology, 191(11), 3615-3622 (2009-04-07)
    A genetic screen for suppressors of bile sensitivity in DNA adenine methylase (dam) mutants of Salmonella enterica serovar Typhimurium yielded insertions in an uncharacterized locus homologous to the Escherichia coli asmA gene. Disruption of asmA suppressed bile sensitivity also in
    Ernst Seiffert et al.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 24(36), 7829-7836 (2004-09-10)
    Perturbations in the integrity of the blood-brain barrier have been reported in both humans and animals under numerous pathological conditions. Although the blood-brain barrier prevents the penetration of many blood constituents into the brain extracellular space, the effect of such
    Amr Ali Mohamed et al.
    Journal of colloid and interface science, 368(1), 625-628 (2011-12-14)
    Two methods for the preparation of uniform dispersions of dehydrocholic acid of different morphologies are described. In the first case, the drug was dissolved in acetone and then re-precipitated by adding a non-solvent (either water or an aqueous stabilizer solution)

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