Dansylglycine, an HSA drug site II probe, is used for the differentiation and analysis of specific binding sites on serum albumin. Dansylglycine is used to generate chromophore-modified cyclodextrins for use in chemosensor development.
Journal of chromatography. B, Biomedical sciences and applications, 714(1), 39-46 (1998-09-24)
This paper describes sample enrichment in a single levitated droplet for capillary electrophoresis (CE) analysis. The droplet was trapped in an acoustical field. The minute sample volumes needed for the enrichment procedure were precisely handled using a piezoelectric flow-through liquid
Journal of the American Chemical Society, 126(43), 14258-14266 (2004-10-28)
It is important to characterize drug-albumin binding during drug discovery and lead optimization as strong binding may reduce bioavailability and/or increase the drug's in vivo half-life. Despite knowing about the location of human serum albumin (HSA) drug binding sites and
Journal of pharmaceutical and biomedical analysis, 15(9-10), 1477-1482 (1997-06-01)
Separation process in a liquid chromatographic column were visualized and analyzed by a developed chromato-videoscope. The migration aspects were evaluated with successively obtained densitograms. In reversed-phase chromatography, the band widths of each solute band were almost equal fore both weakly
Dansylglycine-modified cyclodextrin (DnsC4-beta-CD) was prepared as a fluorescent host that is capable of being immobilized on a cellulose membrane (DnsC4-beta-CD membrane). DnsC4-beta-CD immobilized on the cellulose membrane decreased its fluorescence intensity with increasing concentration of guest molecules, indicating that the
Journal of inorganic biochemistry, 204, 110963-110963 (2019-12-25)
Four Co(III) ternary complexes with the composition of [(Co(4 N))2(quin)](ClO4)4 or [(Co(4 N))2(quinS)](ClO4)3, where 4 N = tris(2-aminoethyl)amine (tren) or tris(2-pyridylmethyl)amine (tpa), quinH2 = quinizarin (1,4-dihydroxy-9,10-anthraquinone), quinSH3 = quinizarin-2-sulfonic acid (1,4-dihydroxy-9,10-anthraquinone-2-sulfonic acid), were synthesized, characterized and their human serum albumin (HSA) binding capabilities were also tested. The complexes can
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