D0296
N-(2,4-Dinitrophenyl)-Pro-Leu-Gly-Cys(Me)-His-Ala-D-Arg amide
≥95% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C38H57N15O11S
CAS Number:
Molecular Weight:
932.02
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
assay
≥95% (HPLC)
storage temp.
−20°C
SMILES string
CSCC(NC(=O)CNC(=O)C(CC(C)C)NC(=O)C1CCCN1c2ccc(cc2N(=O)=O)N(=O)=O)C(=O)NC(Cc3cnc[nH]3)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(N)=O
Substrates
An "optimized" fluorogenic substrate for collagenase.
Certificates of Analysis (COA)
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J Berman et al.
The Journal of biological chemistry, 267(3), 1434-1437 (1992-01-25)
A strategy is described for the rapid optimization of kcat/Km for protease substrates. Selected positions of a given peptide substrate sequence are varied through synthesis with mixtures of amino acids. Incubation of the resulting peptide mixture with the enzyme of
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