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B7188

Sigma-Aldrich

Blonanserin

≥98% (HPLC)

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5 MG
$88.40
25 MG
$341.00

About This Item

Empirical Formula (Hill Notation):
C23H30FN3
CAS Number:
Molecular Weight:
367.50
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

$88.40


In StockDetails


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Quality Level

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: ≥10 mg/mL

originator

Dainippon Sumitomo

storage temp.

room temp

SMILES string

CCN1CCN(CC1)c2cc(-c3ccc(F)cc3)c4CCCCCCc4n2

InChI

1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3

InChI key

XVGOZDAJGBALKS-UHFFFAOYSA-N

Biochem/physiol Actions

Blonanserin is a D2/5-HT2 receptor antagonist; atypical antipsychotic.

Features and Benefits

This compound was developed by Dainippon Sumitomo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Atsushi Hamuro et al.
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 10(4), 198-200 (2010-12-17)
The aim of the present study was to determine the efficacy, side-effects and tolerability of blonanserin for treating refractory behavioural psychological symptoms of dementia (BPSD). The present study was a 12-week, prospective, structured clinical trial of blonanserin for the treatment
Blonanserin for the treatment of delirium patients at an emergency medical care center: an open-label study.
Koji Kato et al.
Asian journal of psychiatry, 6(2), 182-183 (2013-03-08)
Improvement in quetiapine-induced hypoglycemia following a switch to blonanserin.
Yutaro Suzuki et al.
Psychiatry and clinical neurosciences, 66(4), 370-371 (2012-05-26)
Taro Kishi et al.
Journal of psychiatric research, 47(2), 149-154 (2012-11-08)
There is uncertainty about the efficacy and tolerability of blonanserin in schizophrenia. PubMed, the Cochrane Library databases, PsycINFO, and Google Scholar were searched up to September 2012. A systematic review and meta-analysis of individual patient data from randomized, controlled trials
Yu-Guan Wen et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 903, 46-52 (2012-07-24)
Blonanserin is a novel atypical antipsychotic with highly selective receptor antagonist activity to dopamine D₂ and 5-HT(2A). N-desethyl blonanserin (blonanserin C) is its major active metabolite in human plasma. Herein we report a new highly sensitive, selective, and rapid liquid

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