Serine protease inhibitor; Inhibitor of thrombin and activated factor X (Xa). Effective concentration equimolar with proteinase.
Linkage
Not to be confused with thrombin antiserum.
Unit Definition
One unit is the activity present in 0.1 mL of normal human pooled plasma tested in the presence of 0.1 unit of heparin.
Reconstitution
When reconstituted with 1.0 mL of deionized water, solution will contain a minimum of the stated activity in 0.1 M sodium chloride and 0.02 M Tris, pH 7.5.
Cell death and differentiation, 27(2), 790-807 (2019-07-10)
Neuroblastoma is the most common extra-cranial pediatric solid tumor, responsible for 13-15% of pediatric cancer death. Its intrinsic heterogeneity makes it difficult to target for successful therapy. The adaptor protein p140Cap/SRCIN1 negatively regulates tumor cell features and limits breast cancer
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