This product is not tested for solubility. However, information available in the literature states that Ceftazidime hydrate is soluble in 0.1 M NaOH at 50 mg/mL. This information has not been validated.
A6987
Ceftazidime hydrate
Synonym(s):
1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinum
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About This Item
Empirical Formula (Hill Notation):
C22H22N6O7S2 · xH2O
CAS Number:
Molecular Weight:
546.58 (anhydrous basis)
MDL number:
UNSPSC Code:
51284108
PubChem Substance ID:
NACRES:
NA.85
Pricing and availability is not currently available.
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description
does not contain sodium carbonate
Quality Level
assay
95.0-102.0% anhydrous basis
form
powder or crystals
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].CC(C)(O\N=C(/C(=O)N[C@H]1[C@H]2SCC(C[n+]3ccccc3)=C(N2C1=O)C([O-])=O)c4csc(N)n4)C(O)=O
InChI
1S/C22H22N6O7S2.5H2O/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27;;;;;/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34);5*1H2/b26-13-;;;;;/t14-,18-;;;;;/m1...../s1
InChI key
NMVPEQXCMGEDNH-TZVUEUGBSA-N
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General description
Broad spectrum antibiotic; third generation cephalosporin
Application
Ceftazidime hydrate is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis. It is also used in bacterial susceptibility studies and to select mutant colonies of interest.
Used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions
Cephalosporins, such as ceftazidime , disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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