A5783
Albumin, lactosyl bovine
lyophilized powder
Synonym(s):
Albumin-N-1-(deoxylactitol)
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About This Item
MDL number:
UNSPSC Code:
12352202
form
lyophilized powder
Quality Level
composition
Protein, ~85% biuret
extent of labeling
10-20 mol disaccharide per mol albumin
solubility
H2O: soluble 50 mg/mL
storage temp.
−20°C
General description
The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein has an amazing ability to bind to ligands.[1]
Application
Bovine serum albumin (BSA) is extensively used for drug delivery since it is widely available, cheap and easily purified, has ligand-binding properties, and is widely accepted in the pharmaceutical industry.[2]
Albumin was used in a study to test the transfer mechanism of regulated blood-cerebrospinal fluid in immature rats.[3]
Albumin was used in a study to test the transfer mechanism of regulated blood-cerebrospinal fluid in immature rats.[3]
Biochem/physiol Actions
Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.[1]
Packaging
Package size based on protein content
Physical form
Lyophilized powder containing citrate buffer salts
Preparation Note
Prepared from albumin (A 7638) and α-lactose coupled via reductive amination.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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M D Habgood et al.
The Journal of physiology, 456, 181-192 (1992-10-01)
1. The transfer of albumin between the blood and the cerebrospinal fluid (CSF) has been investigated in neonatal (3 days old) and juvenile (20 days old) rats. At both stages of postnatal development, all of the albumin present in the
Yuangang Zu et al.
International journal of nanomedicine, 8, 1207-1222 (2013-04-10)
The livertaxis of glycyrrhizic acid-conjugated bovine serum albumin (GL-BSA) has been reported in the literature. Now, in this paper, we describe a novel type of drug-targeted delivery system containing 10-hydroxycamptothecin (HCPT) with liver tumor targeting. First, GL was coupled to
Karolina A Majorek et al.
Molecular immunology, 52(3-4), 174-182 (2012-06-09)
Serum albumin (SA) is the most abundant plasma protein in mammals. SA is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules. Due to
Proteins containing reductively aminated disaccharides. Synthesis and chemical characterization.
B A Schwartz et al.
Archives of biochemistry and biophysics, 181(2), 542-549 (1977-06-01)
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