A3097

[Pro¹⁸, Asp²¹]-Amyloid β Protein Fragment 17-21 trifluoroacetate salt

≥98% (HPLC), solid

• Empirical Formula (Hill Notation): C₃₃H₄₃N₅O₈
• CAS Number: 182912-74-9
• Molecular Weight: 637.72
• UNSPSC Code: 12352200
• MDL number: MFCD01862668

Properties

• assay: ≥98% (HPLC)
• form: solid
• UniProt accession no.: P05067
• storage temp.: −20°C
• SMILES string: CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CC(O)=O)C(O)=O
• Gene Information: human ... APP(351)

Description

Biochem/physiol Actions

Inhibits amyloid formation in vitro and amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and blocks amyloid fibrial formation in rat brain.

Inhibits amyloid formation in vitro, prevents amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and completely blocks amyloid fibrial formation in rat brain.