93829

L-Tyrosine

≥99.0% (NT), suitable for ligand binding assays, BioUltra

• Synonym(s): (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-L-alanine
• Linear Formula: 4-(HO)C₆H₄CH₂CH(NH₂)CO₂H
• CAS Number: 60-18-4
• Molecular Weight: 181.19
• Beilstein/REAXYS Number: 392441
• EC Number: 200-460-4
• MDL number: MFCD00002606
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57653577
• NACRES: NA.26

Properties

• product name: L-Tyrosine, BioUltra, ≥99.0% (NT)
• product line: BioUltra
• assay: ≥99.0% (NT)
• form: powder or crystals
• optical activity: [α]20/D −11.5±1.0°, c = 4% in 1 M HCl
• technique(s): ligand binding assay: suitable
• impurities: insoluble matter, passes filter test; ≤0.5% foreign amino acids
• ign. residue: ≤0.1%
• loss: ≤0.2% loss on drying, 20 °C (HV)
• color: white
• mp: >300 °C (dec.) (lit.)
• solubility: 1 M HCl: 25 mg/mL, clear, colorless (hot)
• anion traces: chloride (Cl^-): ≤400 mg/kg; sulfate (SO₄^2-): ≤300 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH₄⁺: ≤200 mg/kg; Na: ≤200 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• absorption: cut-off at 310 nm in 1 M HCl at 0.5 M
• SMILES string: N[C@@H](Cc1ccc(O)cc1)C(O)=O
• InChI: 1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
• InChI key: OUYCCCASQSFEME-QMMMGPOBSA-N

Description

Application

L-Tyrosine was used in tyrosine hydroxylase (TH) enzyme activity assay. It was also used as a substrate for tyrosinase enzyme in the growth media of Vibrio cholerae strains to stimulate melanin formation. It may be used as a precursor in the synthesis of (-)-MY 336a. MY 336a, a β-adrenergic receptor antagonist, was initially isolated from the culture broth of Streptomyces gabonae KY2234 (ATCC 15282). It may be used in the synthesis of 3-bromo-L-tyrosine and 3,5-dibromo-L-tyrosine.

Other Notes

Amino acid precursor of dopamine and other catecholamines

Growth requirements of various microorganisms

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves