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93815

Sigma-Aldrich

Rhamnazin

≥99% (HPLC)

Synonym(s):

3′,7-Di-O-methylquercetin, 3′,7-Dimethylquercetin, 3,4′,5-Trihydroxy-3′,7-dimethoxyflavone, Quercetin 3′,7-dimethyl ether

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About This Item

Empirical Formula (Hill Notation):
C17H14O7
CAS Number:
552-54-5
Molecular Weight:
330.29
Beilstein/REAXYS Number:
338203
MDL number:
MFCD00017688
UNSPSC Code:
12352205
PubChem Substance ID:
329770273
NACRES:
NA.25

assay

≥99% (HPLC)

form

powder

SMILES string

COc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3ccc(O)c(OC)c3

InChI

1S/C17H14O7/c1-22-9-6-11(19)14-13(7-9)24-17(16(21)15(14)20)8-3-4-10(18)12(5-8)23-2/h3-7,18-19,21H,1-2H3

InChI key

MYMGKIQXYXSRIJ-UHFFFAOYSA-N

Application

Rhamnazin may be used as a reference material in analysis of plant flavonoids. Rhamnazin and its glycosides may be used to study their potentials as DNA topoisomerase I inhibitors/poisons and as anitoxidants.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M López-Lázaro et al.
Journal of enzyme inhibition and medicinal chemistry, 17(1), 25-29 (2002-10-09)
The therapeutic anticancer potential of flavonoids shown by recent research needs a greater understanding of these compounds. They are antioxidants and antimutagenic agents that can inhibit tumor promotion and transformation and can modify the activity of a large number of
Yao Yu et al.
Biochemical and biophysical research communications, 458(4), 913-919 (2015-02-24)
Anti-angiogenesis targeting vascular endothelial growth factor receptor 2 (VEGFR2) has emerged as an important tool for cancer therapy. The identification of new drugs from natural products has a long and successful history. In this study, we described a novel VEGFR2
B S Yun et al.
Archives of pharmacal research, 23(2), 147-150 (2000-06-03)
Twelve compounds with lipid peroxidation inhibitory activity were isolated from the stem bark of E. globulus. Their structures were assigned as a new aromatic monoterpene (1) and eleven known compounds, pinoresinol (2), vomifoliol (3), 3,4,5-trimethoxyphenol 1-O-beta-D-(6'-O-galloyl)glucopyranoside (4), methyl gallate (5)
M López-Lázaro et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 55(11-12), 898-902 (2001-02-24)
Flavonoids are secondary plant metabolites whose anticancer properties are actually being studied from an epidemiological and pharmacological point of view. They are believed to be implicated in the lower risk of some forms of cancer observed in Asian countries, due
Kayode Ezekiel Adewole
Journal of integrative medicine, 18(2), 92-113 (2020-01-19)
Cancer is a leading cause of death globally, while malaria is the leading cause of death from parasitic diseases in Nigeria. Historically, plant remedies have been used to manage both cancer and malaria. Interestingly, the possibility of treating cancer with
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