30089

L-Cysteine

≥98.5% (RT), suitable for HPLC, BioUltra

• Synonym(s): (R)-2-Amino-3-mercaptopropionic acid
• Linear Formula: HSCH₂CH(NH₂)CO₂H
• CAS Number: 52-90-4
• Molecular Weight: 121.16
• Beilstein/REAXYS Number: 1721408
• EC Number: 200-158-2
• MDL number: MFCD00064306
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57648406
• NACRES: NA.26

Properties

• product name: L-Cysteine, BioUltra, ≥98.5% (RT)
• product line: BioUltra
• assay: ≥98.5% (RT)
• form: powder or crystals
• optical activity: [α]20/D +8.0±0.5°, c = 5% in 5 M HCl
• technique(s): HPLC: suitable
• impurities: insoluble matter, passes filter test; ≤0.5% foreign amino acids
• ign. residue: ≤0.05% (as SO₄)
• loss: ≤0.05% loss on drying, 20 °C (HV)
• color: white
• mp: 240 °C (dec.) (lit.)
• solubility: 1 M HCl: 1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤100 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH₄⁺: ≤500 mg/kg; Na: ≤100 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in 1 M HCl
• UV absorption: λ: 260 nm A_max: 1.5; λ: 280 nm A_max: 0.2
• SMILES string: N[C@@H](CS)C(O)=O
• InChI: 1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
• InChI key: XUJNEKJLAYXESH-REOHCLBHSA-N

Description

Application

L-Cysteine has been used in quenching of unreacted maleimide during antibody grafting. It has also been used in the preparation of nitrosocysteine stock solution, that has been employed to induce S-nitrosylation to achieve reversible cysteine modification.

Biochem/physiol Actions

Cysteine is one of the functional amino acids that regulates metabolism for growth, reproduction, maintenance and immunity. Cysteine provides the disulfide linkage in proteins. It is directly associated with the transport of sulfur. Taurine, a metabolic product of cysteine acts as an antioxidant and controls the cellular redox state. Cysteine is involved in the formation of hydrogen sulfide that is utilized as a signaling molecule.

NMDA glutamatergic receptor agonist.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves