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07497

Sigma-Aldrich

D-myo-Inositol 2,3,4,5,6-pentakis-phosphate decasodium salt

≥85% (HPLC)

Synonym(s):

L-myo-Inositol 1,2,4,5,6-pentakis-phosphate decasodium salt

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About This Item

Empirical Formula (Hill Notation):
C6H7Na10O21P5
CAS Number:
Molecular Weight:
799.87
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.32

assay

≥85% (HPLC)

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].O[C@H]1[C@H](OP([O-])([O-])=O)[C@@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@@H](OP([O-])([O-])=O)[C@H]1OP([O-])([O-])=O

InChI

1S/C6H17O21P5.10Na/c7-1-2(23-28(8,9)10)4(25-30(14,15)16)6(27-32(20,21)22)5(26-31(17,18)19)3(1)24-29(11,12)13;;;;;;;;;;/h1-7H,(H2,8,9,10)(H2,11,12,13)(H2,14,15,16)(H2,17,18,19)(H2,20,21,22);;;;;;;;;;/q;10*+1/p-10/t1-,2-,3-,4+,5-,6-;;;;;;;;;;/m0........../s1

InChI key

GFGCWCIISVRGOQ-HSYGTAAMSA-D

Biochem/physiol Actions

D-myo-Inositol 2,3,4,5,6-pentakis-phosphate was shown to be a ligand for the pleckstrin PH domain.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Sean G Jackson et al.
BMC structural biology, 7, 80-80 (2007-11-24)
Pleckstrin homology (PH) domains are one of the most prevalent domains in the human proteome and represent the major phosphoinositide-binding module. These domains are often found in signaling proteins and function predominately by targeting their host proteins to the cell
Christopher J Barker et al.
Methods in molecular biology (Clifton, N.J.), 645, 1-19 (2010-07-21)
Inositides have an important impact on diverse areas of cellular regulation. However, since this area has grown exponentially from the mid 1980s onwards, many workers find themselves relatively new to the field. In this chapter, we establish a broad foundation

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