Skip to Content
MilliporeSigma
All Photos(1)

Documents

338826

Sigma-Aldrich

Acetic acid

glacial, ≥99.99% trace metals basis

Synonym(s):

Glacial acetic acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3CO2H
CAS Number:
64-19-7
Molecular Weight:
60.05
Beilstein/REAXYS Number:
506007
EC Number:
200-580-7
MDL number:
MFCD00036152
UNSPSC Code:
12352106
PubChem Substance ID:
329754692
NACRES:
NA.21

agency

suitable for ASTM® 7969
suitable for ASTM® 7979
suitable for DIN 38407-43
suitable for EPA 1634
suitable for EPA 534
suitable for EPA 8328
suitable for EPA ACB B21-03
suitable for ISO 21675 2019
suitable for ISO 25101
suitable for ISO/CEN 15968-2011

Quality Level

100

vapor density

2.07 (vs air)

assay

≥99.99% trace metals basis

form

liquid

autoignition temp.

800 °F

expl. lim.

16 %, 92 °F
4 %, 59 °F

technique(s)

HPLC: suitable

refractive index

n20/D 1.371 (lit.)

pH

2.5 (20 °C, 50 g/L)

bp

117-118 °C (lit.)

mp

16.2 °C (lit.)

density

1.04 g/mL at 25 °C (lit.)

SMILES string

[F2C(F2C)13F3C]C(O)=O

InChI

1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

Inchi Key

QTBSBXVTEAMEQO-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Acetic acid can be used as a catalyst:
  • For the solvent-free one-pot condensation of indoles with aryl or heteroaryl aldehydes to synthesize di(indolyl)methanes.
  • In the Pictet-Spengler reaction of substituted tryptamines with cyclic ketones to synthesize tetrahydrospiro-Ͱ-carbolines.
  • To synthesize trisubstituted thiazoles via domino multicomponent reaction.

It can also be used as a:
  • solvent to synthesize aryl amine-functionalized 1,3,5-triazine derivatives via aryl amination of cyanuric chloride with aromatic amines.

Legal Information

ASTM is a registered trademark of American Society for Testing and Materials

Pictograms

FlameCorrosion
GHS02,GHS05

signalword

Danger

hcodes

H226,H314

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

102.2 °F - closed cup

flash_point_c

39 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Katharine Trenholme et al.
Antimicrobial agents and chemotherapy, 58(7), 3666-3678 (2014-04-16)
Therapies to prevent transmission of malaria parasites to the mosquito vector are a vital part of the global malaria elimination agenda. Primaquine is currently the only drug with such activity; however, its use is limited by side effects. The development
Grete Andersen et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 308(2), R123-R130 (2014-11-21)
In healthy individuals, postexercise protein supplementation increases muscle protein anabolism. In patients with muscular dystrophies, aerobic exercise improves muscle function, but the effect of exercise on muscle protein balance is unknown. Therefore, we investigated 1) muscle protein balance before, during
Isabelle Brunet et al.
The Journal of clinical investigation, 124(7), 3230-3240 (2014-06-18)
Autonomic sympathetic nerves innervate peripheral resistance arteries, thereby regulating vascular tone and controlling blood supply to organs. Despite the fundamental importance of blood flow control, how sympathetic arterial innervation develops remains largely unknown. Here, we identified the axon guidance cue
Janani Ramaswamy et al.
Biomaterials, 73, 120-130 (2015-09-26)
Functionalization of biomaterials with material- and cell-specific peptide sequences allows for better control of their surface properties and communication with the surrounding environment. Using a combinatorial phage display approach, we previously identified the peptide VTKHLNQISQSY (VTK) with specific affinity to
Ilya Chumakov et al.
Orphanet journal of rare diseases, 9, 201-201 (2014-12-11)
Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common inherited sensory and motor peripheral neuropathy. It is caused by PMP22 overexpression which leads to defects of peripheral myelination, loss of long axons, and progressive impairment then disability. There is no
View All Related Papers

Articles

Analysis: Activated Nucleotide Sugars by LC-MS/MS

LC-MS/MS method quantifies similar polar nucleotide activated sugars using Supel™ Carbon LC column for simultaneous analysis.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service