T7875
Thiourea
ReagentPlus®, ≥99.0%
Synonym(s):
Sulfourea, Thiocarbamide
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About This Item
Linear Formula:
NH2CSNH2
CAS Number:
Molecular Weight:
76.12
Beilstein/REAXYS Number:
605327
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21
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Quality Level
product line
ReagentPlus®
assay
≥99.0%
mp
170-176 °C (lit.)
SMILES string
NC(N)=S
InChI
1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)
InChI key
UMGDCJDMYOKAJW-UHFFFAOYSA-N
Gene Information
mouse ... Ephx2(13850)
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General description
Thiourea is an analogue of urea, containing sulphur.
Application
Thiourea has been used:
- as a component in ice cold sample buffer for protein analysis
- in intracellular extraction buffer for the extraction of soluble intracellular proteins
- as a component of electrophoresis buffer
Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins
Biochem/physiol Actions
Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea, which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
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Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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