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I0330000

Iopanoic acid

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-(3-Amino-2,4,6-triiodobenzyl)butyric acid, 3-(3-Amino-2,4,6-triiodophenyl)-2-ethylpropanoic acid, Iodopanoic acid

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About This Item

Empirical Formula (Hill Notation):
C11H12I3NO2
CAS Number:
96-83-3
Molecular Weight:
570.93
MDL number:
MFCD00038687
UNSPSC Code:
41116107
PubChem Substance ID:
329815308
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

iopanoic acid

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O=C(O)C(CC)CC1=C(I)C(N)=C(I)C=C1I

InChI

1S/C11H12I3NO2/c1-2-5(11(16)17)3-6-7(12)4-8(13)10(15)9(6)14/h4-5H,2-3,15H2,1H3,(H,16,17)

InChI key

OIRFJRBSRORBCM-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Iopanoic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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A Colantuoni et al.
American journal of physiology. Heart and circulatory physiology, 288(4), H1931-H1936 (2004-12-04)
The aim of the present study was to assess the effects of topically applied triiodothyronine (T(3)) and thyroxine (T(4)) on the arterioles of hamster cheek pouch microcirculation in vivo. Microvessels were visualized using a fluorescent microscopy technique. Topical application of
Joshua D Safer et al.
Thyroid : official journal of the American Thyroid Association, 19(2), 181-185 (2009-02-05)
Although cutaneous manifestations associated with thyroid dysfunction are classic, the potential for thyroid hormone or its antagonists to treat dermatological disease has not been explored with rigor. The predominant circulating thyroid hormone is the pro-hormone, thyroxine (T(4)). Skin, like many
C S Bal et al.
The Journal of clinical endocrinology and metabolism, 90(12), 6536-6540 (2005-09-29)
Telepaque [iopanoic acid (IA)] is believed to rapidly ameliorate hyperthyroidism; however, it may preclude subsequent 131I therapy, possibly delaying it for several months. Our objective was to see how early patients, made euthyroid with Telepaque, can be treated with 131I
Fernando Lizcano et al.
Clinical and experimental pharmacology & physiology, 35(9), 1085-1090 (2008-05-29)
To investigate the effects of iopanoic acid (IA) and carbimazole on increased activity of the hypothalamic-pituitary-adrenal (HPA) axis in hyperthyroidism, we studied 14 women with hyperthyroidism caused by Graves' disease (n + 11) or toxic multinodular goitre (n + 3)
Rossella Monteforte et al.
The Journal of experimental biology, 211(Pt 4), 606-612 (2008-02-05)
The secretory activity of the Harderian gland (HG) is influenced by both exogenous (such as light and temperature) and endogenous (such as prolactin, thyroid hormones and steroid hormones) factors, which vary among species. In the present study, the effects of
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