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Supelco

Orientin

analytical standard

Synonym(s):

8-β-D-Glucopyranosyl-3′,4′,5,7-tetrahydroxyflavone, Luteolin 8-C-β-D-glucopyranoside, Luteolin-8-glucoside, Lutexin

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About This Item

Empirical Formula (Hill Notation):
C21H20O11
CAS Number:
Molecular Weight:
448.38
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:

grade

analytical standard

Quality Level

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤5.0% water

application(s)

food and beverages

format

neat

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccc(O)c(O)c4

InChI

1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1

InChI key

PLAPMLGJVGLZOV-VPRICQMDSA-N

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General description

Orientin is a flavone existing in a variety of plants and exhibits a broad-spectrum of pharmacological properties such as free-radical inhibition, antiviral, radioprotection, anti-oxidant and vasorelaxant property.

Application

Orientin may be used as an analytical reference standard for the quantification of the analyte in leaves of Cecropia species and biological samples using various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Flavonoid glycoside found in the acai tree and globe and passion flowers. Antiviral, antimicrobial and antioxidant. Exhibits radioprotective activities.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificates of Analysis (COA)

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Determination and pharmacokinetics of orientin in rabbit plasma by liquid chromatography after intravenous administration of orientin and Trollius chinensis Bunge extract
Li X, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 853(1-2), 221-226 (2007)
An HPLC-DAD method to quantification of main phenolic compounds from leaves of Cecropia species
Costa.MG, et al.
Journal of the Brazilian Chemical Society, 22(6), 1096-1102 (2011)
Anwarul Hassan Gilani et al.
Basic & clinical pharmacology & toxicology, 99(5), 365-373 (2006-11-02)
Rooibos tea has been widely used for abdominal spasm and diarrhoea. The aim of the present study was to explore the possible mechanism for its use in such ailments. Its aqueous extract (RT) at 0.3-10 mg/ml produced relaxation of spontaneous
Na Lu et al.
Planta medica, 77(10), 984-991 (2011-02-02)
In this study, we provide new evidence that orientin from bamboo leaves (Phyllostachys nigra) protect H9c2 cardiomyocytes against ischemia/reperfusion (I/R) injury through the mitochondrial apoptotic pathway. A previous work has identified that orientin could protect myocardium against ischemia/reperfusion injury. Mitochondria
X-C Fu et al.
Journal of Asian natural products research, 8(3), 265-272 (2006-07-26)
We investigated the anti-apoptotic effect of orientin, from bamboo leaves (Phyllostachys nigra), on rat heart after treatment with ischemia/reperfusion (I/R), and on rat cardiomyocytes injured by hypoxia/reoxygenation (H/R). I/R injury was induced by occluding the left anterior descending coronary artery

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