34750

2,6-Di-tert-butyl-4-methylphenol

purum, ≥99.0% (GC)

• Synonym(s): 2,6-Di-tert-butyl-p-cresol, BHT, Butylated hydroxytoluene, Butylhydroxytoluene, DBPC
• Linear Formula: [(CH₃)₃C]₂C₆H₂(CH₃)OH
• CAS Number: 128-37-0
• Molecular Weight: 220.35
• Beilstein/REAXYS Number: 1911640
• EC Number: 204-881-4
• MDL number: MFCD00011644
• UNSPSC Code: 12352100
• PubChem Substance ID: 329755054
• NACRES: NA.22

Properties

• vapor density: 7.6 (vs air)
• Quality Level: 200
• vapor pressure: <0.01 mmHg ( 20 °C)
• grade: purum
• assay: ≥99.0% (GC)
• autoignition temp.: 878 °F
• bp: 265 °C (lit.)
• mp: 68-72 °C; 69-73 °C (lit.)
• solubility: methanol: 0.1 g/mL, clear, colorless; methanol: soluble 100 mg/mL, clear, colorless
• SMILES string: Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
• InChI: 1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3
• InChI key: NLZUEZXRPGMBCV-UHFFFAOYSA-N
• Gene Information: human ... CAPN1(823) ; rat ... Capn1(29153) , Nos1(24598)

Description

General description

2,6-Di-tert-butyl-4-methylphenol is an 4-alkylphenol. It is an antioxidant and exhibit toxicities mediated by oxidative metabolism to electrophilic quinone methides. It acts as Michael acceptor and its reaction with simple nucleophiles and proteins have been reported. Reaction of 2,6-di-tert-butyl-4-methylphenol with ytterbium(II)-benzophenone dianion complex has been reported. 2,6-Di-tert-butyl-4-methylphenol, a food additive, promotes acute pulmonary toxicity and tumor growth in mice.

Application

2,6-Di-tert-butyl-4-methylphenol may be used in the preparation of an organoaluminum compound, methylaluminum bis(2,6-di-tert-butyl-4-alkylphenoxide).

Safety Information

• pictograms: GHS09
• signalword: Warning
• hcodes: H410
• pcodes: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: 260.6 °F - open cup
• flash_point_c: 127 °C - open cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves