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32991

Supelco

Lanoconazole

VETRANAL®, analytical standard

Synonym(s):

2-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile

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About This Item

Empirical Formula (Hill Notation):
C14H10ClN3S2
CAS Number:
101530-10-3
Molecular Weight:
319.83
MDL number:
MFCD00865590
UNSPSC Code:
41116107
PubChem Substance ID:
329754426
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

Clc1ccccc1C2CS\C(S2)=C(\C#N)n3ccnc3

InChI

1S/C14H10ClN3S2/c15-11-4-2-1-3-10(11)13-8-19-14(20-13)12(7-16)18-6-5-17-9-18/h1-6,9,13H,8H2/b14-12+

InChI key

ZRTQSJFIDWNVJW-WYMLVPIESA-N

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General description

Lanoconazole is a member of the imidazole family and an antifungal agent, which finds applications as an antidermatophytic drug.

Application

Lanoconazole may be used as a reference standard in the determination of lanoconazole in pharmaceutical formulations using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC-UV).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG1057
BCCC4640
BCBV5216
SZBE022XV
SZBA203X

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Allergic contact dermatitis due to lanoconazole with no cross-reactivity to other imidazoles.
S Taniguchi et al.
Dermatology (Basel, Switzerland), 196(3), 366-366 (1998-06-11)
Yoshiyuki Tatsumi et al.
Microbiology and immunology, 46(7), 433-439 (2002-09-12)
We developed a new technique for culture study that successfully recovers fungi from drug-treated skin tissues, in which tissue specimens were homogenized, dialyzed against water, digested with trypsin, and then washed with PBS, to eliminate the drug that remaining in
Toshihiro Akihisa et al.
Journal of oleo science, 59(7), 351-360 (2010-06-02)
The content and composition of triterpene alcohol fractions of the non-saponifiable lipids (NSL) along with the fatty acid composition of the kernel fats (n-hexane extracts) of the shea tree (Vitellaria paradoxa; Sapotaceae) were determined for 36 samples from seven sub-Saharan
Daisuke Todokoro et al.
Cornea, 38(2), 238-242 (2018-11-14)
Fungal keratitis can be difficult to medically treat. Topical antifungals are usually applied empirically as the initial option in treating fungal keratitis. Natamycin (NAT) and/or voriconazole (VRCZ) have been widely used in the treatment of fungal keratitis. However, Fusarium solani
Application of experimental design for the optimization of forced degradation and development of a validated stability-indicating LC method for luliconazole in bulk and cream formulation.
Sonawane S and Gide P
Arabian Journal of Chemistry, 9, S1428-S1434 (2016)
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