18370

2,2,2-Trifluoroethanol

suitable for mass spectrometry (MS), LiChropur^™, ≥99.8% (GC)

• Synonym(s): Trifluoroethyl alcohol
• Linear Formula: CF₃CH₂OH
• CAS Number: 75-89-8
• Molecular Weight: 100.04
• Beilstein/REAXYS Number: 1733203
• EC Number: 200-913-6
• MDL number: MFCD00004672
• UNSPSC Code: 41116105

Properties

• vapor density: 3.5 (vs air)
• Quality Level: 100
• vapor pressure: 70 mmHg ( 25 °C)
• assay: ≥99.8% (GC)
• form: liquid
• autoignition temp.: ~896 °F
• expl. lim.: 42 %
• manufacturer/tradename: LiChropur^™
• technique(s): HPLC: suitable; mass spectrometry (MS): suitable
• refractive index: n20/D 1.3 (lit.)
• bp: 77-80 °C (lit.)
• mp: −44 °C (lit.)
• density: 1.390-1.392 g/mL at 20 °C; 1.373 g/mL at 25 °C (lit.)
• cation traces: Al: ≤0.5 mg/kg; Ba: ≤0.1 mg/kg; Bi: ≤0.1 mg/kg; Ca: ≤0.5 mg/kg; Cd: ≤0.05 mg/kg; Co: ≤0.02 mg/kg; Cr: ≤0.02 mg/kg; Cu: ≤0.02 mg/kg; Fe: ≤0.1 mg/kg; K: ≤0.5 mg/kg; Li: ≤0.1 mg/kg; Mg: ≤0.1 mg/kg; Mn: ≤0.02 mg/kg; Mo: ≤0.1 mg/kg; Na: ≤1 mg/kg; Ni: ≤0.02 mg/kg; Pb: ≤0.1 mg/kg; Sr: ≤0.1 mg/kg; Zn: ≤0.1 mg/kg
• suitability: complies for LC-MS
• SMILES string: OCC(F)(F)F
• InChI: 1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2
• InChI key: RHQDFWAXVIIEBN-UHFFFAOYSA-N

Description

General description

• 2,2,2-Trifluoroethanol is commonly used as a mobile phase additive in liquid chromatography-mass spectrometry (LC-MS).

Features:

• Extensive QC testing ensures the highest specifications.,·        
• Optimized to improve ionization and resolution.
• Extremely low levels of inorganic and organic impurities.      
• Manufactured specifically for accurate and fast LC-MS.

Application

2,2,2-Trifluoroethanol may be used as a solvent in the development of a sample preparation method for the detection of high-mass proteins in tissue samples using matrix-assisted laser desorption/ionization mass spectrometry technique. It may also be used as a mobile phase modifier for the analysis and purification of alcohol-sensitive chiral compounds using supercritical fluid chromatography (SFC) technique.

Packaging

Clear borosilicate glass, high hydrolytic resistance (Type I)

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS06,GHS08,GHS05
• signalword: Danger
• hcodes: H226,H301 + H331,H318,H360F,H373
• pcodes: P202 - P210 - P280 - P301 + P310 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - STOT RE 2 Inhalation
• target_organs: Blood
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 86.0 °F - closed cup
• flash_point_c: 30 °C - closed cup