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Sigma-Aldrich

D-(+)-Glucose monohydrate

meets analytical specification of Ph. Eur., BP, Ph Franç., 97.5-102.0% anhydrous basis(HPLC)

Synonym(s):

Dextrose monohydrate

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About This Item

Empirical Formula (Hill Notation):
C6H12O6 · H2O
CAS Number:
14431-43-7
Molecular Weight:
198.17
Beilstein/REAXYS Number:
5250278
EC Number:
218-914-5
MDL number:
MFCD00149450
UNSPSC Code:
12352201
PubChem Substance ID:
57647555
NACRES:
NA.21

assay

97.5-102.0% anhydrous basis (HPLC)

Quality Level

200

form

powder

optical activity

[α]20/D +52.5 to +53.3°, c = 10% in H2O (calc. on anhydrous subst.)

quality

meets analytical specification of Ph. Eur., BP, Ph Franç.

impurities

residual solvents, complies
97.5-102.0% anhydrous basis (HPLC)

ign. residue

≤0.1% (as SO4)

color

white

useful pH range

6-7 (20 °C, 100 g/L)

mp

~83  °C (181 °F )

solubility

H2O: 10g/5 mL, clear, colorless

anion traces

chloride (Cl-): ≤100 mg/kg
sulfite (SO32-): ≤15 ppm

cation traces

Al: ≤0.5 mg/kg
As: ≤1 mg/kg
Ba:, in accordance
Ca: ≤200 mg/kg
Pb: ≤0.5 mg/kg

SMILES string

O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O

InChI

1S/C6H12O6.H2O/c7-1-3(9)5(11)6(12)4(10)2-8;/h1,3-6,8-12H,2H2;1H2/t3-,4+,5+,6+;/m0./s1

InChI key

SPFMQWBKVUQXJV-BTVCFUMJSA-N

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Application

D-(+)-Glucose monohydrate has been used as a test compound for studying its dehydration kinetics by using THz time-domain spectroscopy (THz-TDS).

Biochem/physiol Actions

D-(+)-Glucose is a common natural sugar involved in key cellular processes of energy production, glycosylation and formation of glycans that provide structure to cells. Glucose is involved in post-translational modifications of proteins by glycation or non-enzymatic glycosylation of proteins at the lysine residues. Glycation is detrimental and results in complications associated with diabetes mellitus, alzheimer′s disease, aging and cataract.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
STBL1513
STBL2370
STBL2369
STBK8903
STBK7210

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Dehydration kinetics of D-glucose monohydrate studied using THz time-domain spectroscopy.
Hai-Bo Liu
Chemical Physics Letters, 429 (2006)
Marta Pajares et al.
Autophagy, 12(10), 1902-1916 (2016-07-19)
Autophagy is a highly coordinated process that is controlled at several levels including transcriptional regulation. Here, we identify the transcription factor NFE2L2/NRF2 (nuclear factor, erythroid 2 like 2) as a regulator of autophagy gene expression and its relevance in a
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose.
Thornalley PJ et al
The Biochemical Journal, 344 (1999)
Codruta Ignea et al.
Nature communications, 10(1), 3799-3799 (2019-08-25)
Synthetic biology efforts for the production of valuable chemicals are frequently hindered by the structure and regulation of the native metabolic pathways of the chassis. This is particularly evident in the case of monoterpenoid production in Saccharomyces cerevisiae, where the
Mickael Cregut et al.
Environmental science and pollution research international, 29(1), 1037-1050 (2021-08-04)
Characterizing waste ecotoxicity is laborious because of both the undefined nature of environmental samples and the diversity of contaminants that can be present. With regard to these limitations, traditional approaches do not provide information about the nature of the pollution
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