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12832

Sigma-Aldrich

3-(2-Benzoxazolyl)umbelliferyl acetate

for fluorescence, ≥98.0% (HPLC)

Synonym(s):

7-Acetoxy-3-(2-benzoxazolyl)coumarin

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About This Item

Empirical Formula (Hill Notation):
C18H11NO5
CAS Number:
Molecular Weight:
321.28
Beilstein/REAXYS Number:
5985817
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

grade

for fluorescence

assay

≥98.0% (HPLC)

mp

203-205 °C (lit.)

solubility

DMF: soluble
DMSO: soluble
dioxane: soluble

fluorescence

λex 410 nm; λem 468 nm in 50 mM Tris pH 8.0 (esterase)

storage temp.

2-8°C

SMILES string

CC(=O)Oc1ccc2C=C(C(=O)Oc2c1)c3nc4ccccc4o3

Application

The reagent has absorption maxima in the UV range but weak blue fluorescence; however, enzymatic hydrolysis converts it into highly fluorescent anionic molecule.
suitable as fluorogenic substrate for esterases

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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