12279

1,2-Propanediol

analytical standard

• Synonym(s): 1,2-PDO, Propylene glycol
• Linear Formula: CH₃CH(OH)CH₂OH
• CAS Number: 57-55-6
• Molecular Weight: 76.09
• Beilstein/REAXYS Number: 1340498
• EC Number: 200-338-0
• MDL number: MFCD00064272
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749683
• E Number: E490
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• vapor density: 2.62 (vs air)
• vapor pressure: 0.08 mmHg ( 20 °C)
• assay: ≥99.7% (GC)
• autoignition temp.: 779 °F
• shelf life: limited shelf life, expiry date on the label
• expl. lim.: 12.5 %
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• refractive index: n20/D 1.432 (lit.); n20/D 1.433
• bp: 187 °C (lit.)
• mp: −60 °C (lit.)
• density: 1.036 g/mL at 25 °C (lit.)
• application(s): cleaning products; cosmetics; environmental; flavors and fragrances; food and beverages; forensics and toxicology; personal care; pharmaceutical (small molecule)
• format: neat
• SMILES string: CC(O)CO
• InChI: 1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
• InChI key: DNIAPMSPPWPWGF-UHFFFAOYSA-N

Description

General description

1,2-Propanediol is a compound found to be chemically similar to ethylene glycol and is widely used in automobile antifreeze, activated charcoal preparations, cosmetics, beverages, ointments, etc. It is used as a diluent for the intravenous preparations of poorly water-soluble drugs.

This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food.

Find all available reference materials for compounds listed in 10/2011 here

Application

1,2-Propanediol may be used as an analyte protectant for the gas chromatography-mass spectrometric detection of environmental contaminants in honey, honeybees and pollens. It is also used as an analytical reference standard for the quantification of the analyte in biological fluids using headspace-gas chromatography (HS-GC) technique.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 217.4 °F - closed cup
• flash_point_c: 103 °C - closed cup
• ppe: Eyeshields, Gloves