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03989

Sigma-Aldrich

Eukitt® Quick-hardening mounting medium

for microscopy

Synonym(s):

Poly(butyl methacrylate-co-methyl methacrylate)

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About This Item

Linear Formula:
[CH2C(CH3)[CO2(CH2)3CH3]]X[CH2C(CH3)(CO2CH3)]Y
CAS Number:
MDL number:
UNSPSC Code:
41116121
PubChem Substance ID:
NACRES:
MA.02

grade

for microscopy

Quality Level

form

liquid

color

yellow

refractive index

n/D 1.490-1.500

viscosity

250-500 mPa.s, neat(25 °C)(lit.)

solubility

water: insoluble

suitability

in accordance for application

application(s)

hematology
histology

storage temp.

room temp

SMILES string

COC(=O)C(C)=C.CCCCOC(=O)C(C)=C

InChI

1S/C8H14O2.C5H8O2/c1-4-5-6-10-8(9)7(2)3;1-4(2)5(6)7-3/h2,4-6H2,1,3H3;1H2,2-3H3

InChI key

WHLPIOPUASGRQN-UHFFFAOYSA-N

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General description

Eukitt® Quick-hardening mounting medium, or Poly(butyl methacrylate-co-methyl methacrylate), is a mounting medium for microscopy, containing 45% acrylic resin and 55% xylenes. It is a special-purpose adhesive, sealant, and specimen preservative that can be used manually and in automated cover-slipping equipment, glass, non-plastic, and other non-reactive materials.

Application

  • It has been used in histomorphometry to study the use of gambogic amide for augmenting skeletal adaptation to mechanical forces without inducing hyperalgesia.
  • It has been used in immunohistochemistry and immunofluorescence to document the global location of coxsackievirus and adenovirus receptors in the mouse brain.
  • It has been used in immunocytochemistry to study the function of matrix metalloproteinases in regulating cancer invasiveness.

Features and Benefits

  • Spreads quickly and evenly without forming any air bubbles.
  • Non-yellowing, unaffected by cold, and stays optically clear for over 10 years.

Physical properties

Fast-drying (20 minutes), Refractive index close to that of glass (1.510), chemically neutral, little sensitivity to water, no reaction to staining, temperature limits: 42°C-17°C, not affected by ultraviolet light, non yellowing, unaffected by cold, stays optically clear for over 10 years, can be used in place of epoxy resins for mounting petrographic thin sections, used in fluorescence dyes in bones.

Legal Information

Eukitt is a registered trademark of Orsatec GmbH

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Danger

Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

target_organs

Central nervous system,Liver,Kidney, Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

73.4 °F - closed cup

flash_point_c

23 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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The TrkA agonist gambogic amide augments skeletal adaptation to mechanical loading
Fioravanti, et al.
Bone (2021)
Gabriella Fioravanti et al.
Bone, 147, 115908-115908 (2021-03-14)
The periosteal and endosteal surfaces of mature bone are densely innervated by sensory nerves expressing TrkA, the high-affinity receptor for nerve growth factor (NGF). In previous work, we demonstrated that administration of exogenous NGF significantly increased load-induced bone formation through
Sílvia Coimbra et al.
Journal of experimental botany, 60(11), 3133-3142 (2009-05-13)
Arabinogalactan proteins (AGPs) are structurally complex plasma membrane and cell wall proteoglycans that are implicated in diverse developmental processes, including plant sexual reproduction. Male gametogenesis (pollen grain development) is fundamental to plant sexual reproduction. The role of two abundant, pollen-specific
Ulrich Andergassen et al.
Oncology reports, 37(5), 3055-3060 (2017-04-26)
Triple-negative breast cancer is a highly aggressive type of mammalian carcinoma. It is defined by a rather weak expression of estrogen-, progesterone- and Her2-receptor, and is thus difficult to treat, resulting in low disease-free and overall survival rates of the
Baihui Li et al.
Journal of autoimmunity, 90, 132-145 (2018-03-01)
Sjögren's syndrome is a multifactorial systemic autoimmune disorder characterized by lymphocytic infiltrates in exocrine organs. Patients present with sicca symptoms, such as extensive dry eyes and dry mouth, and parotid enlargement. Other serious complications include profound fatigue, chronic pain, major

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