The Journal of investigative dermatology, 135(8), 2077-2083 (2015-04-02)
Epigenetic modifications by DNA methylation are associated with a wide range of diseases. Previous studies in psoriasis have concentrated on epigenetic changes in immune cells or in total skin biopsies that include stromal-associated changes. In order to improve our understanding
Journal of immunology (Baltimore, Md. : 1950), 181(2), 1109-1119 (2008-07-09)
To elucidate the mechanisms controlling peripheral tolerance, we established two transgenic (Tg) mouse strains expressing different levels of membrane-bound OVA (mOVA) as a skin-associated self-Ag. When we transferred autoreactive TCR-Tg CD8 T cells (OT-I cells), keratin 14 (K14)-mOVA(high) Tg mice
Journal of molecular graphics & modelling, 28(2), 183-186 (2009-07-25)
Cyanide (CN) is considered to be a terrorist chemical weapon due to its ready availability in multi-kilogram quantities and multi-modal means of intoxication. The body uses the sulfur transferase enzyme rhodanese to detoxify cyanide via conversion of cyanide to thiocyanate.
The velocity fields within the impeller passages of three different impellers of the Kyoto-NTN bio-centrifugal ventricular assist device are measured using laser Doppler velocimetry in this study. The 16 forward-swept-blade impeller has better performance than the 16 straight-blade and 8
As global transcriptome analyses with a growing demand on layer-specific applications are widely used in cutaneous biology, we investigated the effect of established and optimized dermo-epidermal separation methods on the quality of RNA. We compared enzymatic separation with dispase, chemical
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