MABT196

Anti-Endoplasmin GRP94 Antibody, clone 10C1.2

clone 10C1.2, from mouse

• Synonym(s): Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1, gp96 homolog
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 10C1.2, monoclonal
• species reactivity: human
• technique(s): immunohistochemistry: suitable; western blot: suitable
• isotype: IgG2aκ
• NCBI accession no.: NP_003290
• UniProt accession no.: P14625
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... HSP90B1(7184)

Description

General description

94 kDa glucose-regulated protein (GRP94) is also called Endoplasmin, Heat shock protein 90 kDa beta member 1 (HSP90B1), Tumor rejection antigen 1 (TRA1) and gp96 homolog. GRP94 is involved in the processing and transport of secreted proteins. GRP94 also functions in endoplasmic reticulum associated degradation (ERAD), and has ATPase activity.

Immunogen

Epitope: C-terminus

GST-tagged recombinant protein corresponding to the C-terminus of human Endoplasmin GRP94.

Application

Anti-Endoplasmin GRP94 Antibody, clone 10C1.2 is a highly specific mouse monoclonal antibody, that targets Glucose-Regulated Protein 94 & has been tested in western blotting & IHC.

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Endoplasmin GRP94 in human lung section tissue.

Research Category
Cell Structure

Research Sub Category
Adhesion (CAMs)

Quality

Evaluated by Western Blotting in human lung tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Endoplasmin GRP94 in 10 µg of human lung tissue lysate.

Target description

~94 kDa observed

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable