MABN502

Anti-SNAT1 Antibody, clone N104/37

clone N104/37, from mouse

• Synonym(s): Sodium-coupled neutral amino acid transporter 1, Amino acid transporter A1, rATA1, Glutamine transporter, N-system amino acid transporter 2, Solute carrier family 38 member 1, System A amino acid transporter 1, System A transporter 2, System N amino acid
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: N104/37, monoclonal
• species reactivity: mouse, human, rat
• technique(s): immunohistochemistry: suitable; western blot: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_620187
• UniProt accession no.: Q9JM15
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SLC38A1(81539)

Description

General description

Sodium-coupled neutral amino acid transporter 1 (SNAT) is also called, Amino acid transporter A1 (ATA1), Glutamine transporter (Glnt), N-system amino acid transporter 2, Solute carrier family 38 member 1 (SLC38A1), System A amino acid transporter 1 (SAT1), System A transporter 2 (SA2), and System N amino acid transporter 1. SNAT functions as a sodium-dependent amino acid transporter that may supply glutamatergic and GABAergic neurons with the glutamine required for the synthesis of the neurotransmitters glutamate and GABA. SNAT is specifically expressed in brain, with the highest levels in cerebellum and thalamus, in glutamatergic, GABAergic and dopaminergic neurons, ependymal cells lining the ventricle and is also detected in spinal cord, heart, colon and placenta.

Specificity

This antibody recognizes the N-terminus of SNAT1.

Immunogen

Epitope: N-terminus

Recombinant protein corresponding to the N-terminus of rat SNAT1.

Application

Detect Sodium-coupled neutral amino acid transporter 1 using this mouse monoclonal antibody, Anti-SNAT1 Antibody, clone N104/37 validated for use in western blotting & IHC.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SNAT1 in rat midbrain and human thalamus tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Quality

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected SNAT1 in 10 µg of human brain tissue lysate.

Target description

~ 54 kDa observed

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Human brain tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable