MABD83
Anti-SOX10, clone 12H6.1 Antibody
clone 12H6.1, from mouse
Synonym(s):
SOX-10
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About This Item
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biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
12H6.1, monoclonal
species reactivity
human
technique(s)
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SOX10(6663)
General description
Transcription factor SOX10 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Sox10 acts as a nucleocytoplasmic shuttle protein and is important for neural crest, glial and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
Immunogen
KLH-conjugated linear peptide corresponding to Human SOX10.
Application
Detect SOX10 using this Anti-SOX10 antibody, clone 12H6.1 validated for use in western blotting.
Research Category
Stem Cell Research
Neuroscience
Stem Cell Research
Neuroscience
Research Sub Category
Developmental Neuroscience
Neurodegenerative Diseases
Developmental Neuroscience
Neurodegenerative Diseases
Quality
Evaluated by Western Blot in a SK-MEL-28 cell lysate. Western Blot Analysis: A 1:2000 dilution of this antibody detected SOX10 in a 10 µg SK-MEL-28 cell lysate.
Target description
~55 kDa observed
Physical form
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
SK-MEL-28 cell lysate
SK-MEL-28 cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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