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AG252

Sigma-Aldrich

GAD Peptide

control for AB1511, powder

Synonym(s):

GAD

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.77

product name

GAD, control peptide for AB1511,

biological source

rat

Quality Level

assay

>80%

form

powder

manufacturer/tradename

Chemicon®

technique(s)

cell based assay: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Gene Information

rat ... GAD2(24380)

General description

Synthetic peptide corresponding to amino acid residues Cys+ 572-585 of rat GAD65 (Erlander et al., 1991). The amino acid sequence is wholly conserved in rat GAD67, and the peptide is located at the C-terminus in both forms of the enzyme. Sequence: [C]DFLIEEIERLGQDL.

Application

Antibody blocking (AB1511)

Optimal working dilution must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neuronal & Glial Markers

Physical form

White lyophilized powder. Soluble in water.

Storage and Stability

Long term storage at -20°C in a sealed container with desiccant for up to 12 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M G Erlander et al.
Neuron, 7(1), 91-100 (1991-07-01)
gamma-Aminobutyric acid (GABA) is the most widely distributed known inhibitory neurotransmitter in the vertebrate brain. GABA also serves regulatory and trophic roles in several other organs, including the pancreas. The brain contains two forms of the GABA synthetic enzyme glutamate
Louis-Etienne Lorenzo et al.
Nature communications, 11(1), 869-869 (2020-02-15)
Spinal disinhibition has been hypothesized to underlie pain hypersensitivity in neuropathic pain. Apparently contradictory mechanisms have been reported, raising questions on the best target to produce analgesia. Here, we show that nerve injury is associated with a reduction in the

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