8.22325

4′-Hydroxyacetanilide

for synthesis

• Synonym(s): 4′-Hydroxyacetanilide
• Linear Formula: CH₃CONHC₆H₄(OH)
• CAS Number: 103-90-2
• Molecular Weight: 151.16
• MDL number: MFCD00002328
• UNSPSC Code: 12352111
• EC Index Number: 203-157-5
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: ≥99.0% (HPLC)
• form: powder
• autoignition temp.: 540 °C
• potency: 1944 mg/kg LD₅₀, oral (Rat)
• expl. lim.: 15 % (v/v)
• pH: 5.5-6.5 (20 °C in H₂O, saturated solution)
• mp: 169-170 °C
• solubility: 14 g/L
• density: 1.293 g/cm³ at 21 °C
• storage temp.: 2-30°C
• InChI: 1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)
• InChI key: RZVAJINKPMORJF-UHFFFAOYSA-N

Description

Application

• A Review on the Properties and Uses of Paracetamol: This article provides a comprehensive overview of paracetamol, detailing its critical properties and varied uses in the pharmaceutical industry. (Ogemdi, 2019).


• Development and Validation of a Chromatographic Method for Estimating Paracetamol: Discusses a method for simultaneous estimation of paracetamol and other compounds, highlighting its pharmacological significance. (Navneet Kumar et al., 2017).


• Quality Assessment of Paracetamol Tablets: Evaluates the quality of different brands of paracetamol tablets in the Yemeni market, crucial for consumer safety. (Ali Alyahawi et al., 2018).

Analysis Note

Assay (HPLC, area%): ≥ 99.0 % (a/a)
Melting range (lower value): ≥ 168 °C
Melting range (upper value): ≤ 172 °C
Identity (IR): passes test

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 364.3 °F - Pensky-Martens closed cup
• flash_point_c: 184.6 °C - Pensky-Martens closed cup