172103

Anaphase-Promoting Complex Inhibitor Negative Control, AAME

The Anaphase-Promoting Complex Inhibitor Negative Control, AAME, also referenced under CAS 1784-05-0, controls the biological activity of Anaphase-Promoting Complex.

• Synonym(s): Anaphase-Promoting Complex Inhibitor Negative Control, AAME, AAME hydrochloride
• Empirical Formula (Hill Notation): C₉H₁₈N₄O₃ · xHCl
• CAS Number: 1784-05-0
• Molecular Weight: 230.26 (free base basis)
• UNSPSC Code: 41106609
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥99% (TLC)
• form: powder
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: white
• solubility: water: 50 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: N=C(NCCC[C@@H](C(OC)=O)NC(C)=O)N.[xHCl]
• InChI: 1S/C9H18N4O3.ClH/c1-6(14)13-7(8(15)16-2)4-3-5-12-9(10)11;/h7H,3-5H2,1-2H3,(H,13,14)(H4,10,11,12);1H/t7-;/m0./s1
• InChI key: FIUSXBMWQFBXLZ-FJXQXJEOSA-N

Description

General description

An acetyl-L-arginine analog of TAME that serves as a negative control. TAME is an ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation.

Packaging

Packaged under inert gas

Warning

Toxicity: Regulatory Review (Z)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Zeng, X., et al. 2010. Cancer Cell18, 382.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable