1.07731

Silica gel 60 G

for thin-layer chromatography

• Synonym(s): Silica gel
• CAS Number: 112926-00-8
• MDL number: MFCD00011232
• UNSPSC Code: 41115711
• EC Index Number: 231-545-4
• NACRES: NB.21

Properties

• material: silica gel 60 matrix
• Quality Level: 100
• form: powder
• potency: >5000 mg/kg LD₅₀, skin (Rabbit)
• feature: binder Organic Polymer; fluorescent indicator: no
• packaging: pkg of 25 kg
• technique(s): thin layer chromatography (TLC): suitable
• particle size: 5-40 μm
• pore size: 60 Å medium pore diameter
• pH: 7 (20 °C, 100 g/L in H₂O, slurry)
• bp: 2230 °C
• mp: >1600 °C
• bulk density: 200‑800 kg/m³
• storage temp.: no temp limit
• SMILES string: O=[Si]=O
• InChI: 1S/O2Si/c1-3-2
• InChI key: VYPSYNLAJGMNEJ-UHFFFAOYSA-N

Description

General description

Standardized sorbents ensure reliable results every time. Our broad spectrum meets all kinds of needs. In TLC, silica gel 60 sorbent is considered the most versatile. Our assortment of silica gel 60 features different grades with particle sizes ranging from 5-40 µm: silica with a gypsum binder, silica with no foreign binder, and silica gel with a fluorescence indicator. We also offer high-quality aluminum oxide, cellulose microcrystalline, and kieselgur (also known as diatomaceous earth).

Application

• Development and Validation of Chromatographic Methods for Simultaneous Estimation of Aspirin and Pantoprazole Sodium in Pure and Mixture Form.: This research developed and validated chromatographic methods using Silica gel 60 G for the accurate estimation of aspirin and pantoprazole sodium. The study highlights the gel′s capability in achieving high-resolution separations, crucial for pharmaceutical analysis (Chandarana C et al., 2024).


• Bioactivity profiles of six baobab fruit pulp powders via planar chromatography hyphenated with effect-directed analysis.: Leveraging Silica gel 60 G, this study presented bioactivity profiling of baobab fruit pulp powders. The advanced chromatographic techniques used provided comprehensive insights into the nutritional and medicinal potential of the fruit (Azadniya E et al., 2023).


• Isolation, development and validation of HPTLC method for the estimation of beta-carotene from Gymnosporia senegalensis (Lam.) Loes.: Utilizing Silica gel 60 G, this research established a high-performance thin-layer chromatography (HPTLC) method for quantifying beta-carotene in plant extracts, demonstrating the gel′s effectiveness in natural product research (Jain D et al., 2023).


• Determination of polybrominated diphenyl ethers in marine sediments by composite chromatography column purification-gas chromatography-negative chemical ionization-mass spectrometry.: This study shows the application of Silica gel 60 G in environmental analysis, specifically for the determination of hazardous compounds in marine sediments, underscoring its role in pollution monitoring (Dong JY et al., 2023).

Linkage

Replaces: 1077315003; 1.07731.5003

Analysis Note

pH-value (10% suspension): 6.0 - 7.0
Fe (Iron): ≤ 0.02%
Calcium sulfate (CaSO₄·0.5 H₂O): 12.0 - 13.5%
Application test: conforms
Particle size (Laser diffraction): 90% <55 µm
The data to the particle size are related to the pure Silica gel before additive addition.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable