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Sigma-Aldrich

Anti-MAP2 Antibody, clone 5F9

clone 5F9, Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

5F9, monoclonal

species reactivity

mouse, human, rabbit, rat

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_013066.1

UniProt accession no.

P15146

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... MAP2(4133)
mouse ... Map2(17756)
rat ... Map2(25595)

Specificity

MAP2

Immunogen

Purified rat brain microtubules MAP2

Application

Detect MAP2 using this Anti-MAP2 Antibody, clone 5F9 validated for use in WB, IH.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurofilament & Neuron Metabolism

Quality

routinely evaluated on rat brain microsomal preparation (Catalog #12-144).

Target description

202.41 kDa

Physical form

200 µg of protein G purified mouse IgG1 in 200 µL of storage buffer (0.02 M phosphate buffer, pH 7.6, 0.25 M NaCl, and 0.1% sodium azide. Frozen at -20°C.
Format: Purified
Protein G Chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Description
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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Microtubule-associated protein 2: monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles.
Kosik, K S, et al.
Proceedings of the National Academy of Sciences of the USA, 81, 7941-7945 (1984)
Mototsugu Eiraku et al.
The Journal of biological chemistry, 277(28), 25400-25407 (2002-04-16)
We have identified a novel epidermal growth factor (EGF)-like repeat-containing single-pass transmembrane protein that is specifically expressed in the developing and mature central nervous system. Sequence analysis revealed that the 10 EGF-like repeats in the extracellular domain are closely related
Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis, LTP and spatial memory.
Li, H; Zhong, X; Chau, KF; Williams, EC; Chang, Q
Nature Neuroscience null
Activity-dependent regulation of surface glucose transporter-3.
Ferreira, JM; Burnett, AL; Rameau, GA
The Journal of Neuroscience null
Hui He et al.
Cell biology international, 44(2), 536-548 (2019-10-24)
Valproate (VPA), an effective clinical approved anti-epileptic drug and mood stabilizer, has been believed to induce neuronal differentiation at the expense of inhibiting astrocytic and oligodendrocytic differentiation. Nevertheless, the involving mechanisms of it remain unclear yet. In the present study
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