C-045S

Cannabidiol solution

1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant^®

• Synonym(s): CBD
• Empirical Formula (Hill Notation): C₂₁H₃₀O₂
• CAS Number: 13956-29-1
• Molecular Weight: 314.46
• MDL number: MFCD00869597
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1 mg/mL in methanol
• format: single component solution
• storage temp.: −20°C
• SMILES string: CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1
• InChI: 1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1
• InChI key: QHMBSVQNZZTUGM-ZWKOTPCHSA-N

Description

General description

This certified Snap-N-Spike^® solution is suitable as starting material in the preparation of calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to pharmaceutical research.
Cannabidiol (CBD) is one of the important cannabinoids found in plants of the Cannabaceae family known for its non-psychoactive properties. It forms upon the decarboxylation of its precursor cannabidiolic acid in the presence of light or heat. It shows various therapeutic properties, such as antioxidative, anti-inflammatory, antimicrobial, neuroprotective, anxiolytic, and anticonvulsant.

Application

The Certified Reference Material (CRM) in solution can also be used as follows:

• Determination of four cannabinoids from an oil matrix using reversed-phase high-performance liquid chromatography (RP-HPLC) combined to a diode array detector (DAD)
• Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) based technique to measure cannabidiol, ∆9-tetrahydrocannabinol, and its metabolites in whole blood samples obtained from rats administered a high dose of cannabidiol
• Simultaneous determination of cannabidiol and tetrahydrocannabinol in different hemp oil-containing products using isocratic RP-HPLC coupled with UV detection
• Multi-analysis of hair samples for Δ9-tetrahydrocannabinol, cannabinol, and cannabidiol by liquid-liquid extraction (LLE) followed by gas chromatography-mass spectrometry-based quantification
• Ultrasound-assisted extraction of cannabidiol from three different commercial topical products followed by GC-MS based determination

Features and Benefits

• Fully characterized under ISO/IEC 17025and ISO 17034 accreditation
• Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
• Rigorously tested through real-time stability studies to ensure accuracy and shelf life
• Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
• Flame sealed under argon into ampoules for long-term shelf life
• Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes,Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup