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858141P

Avanti

17:1 Lyso PS

1-(10Z-heptadecenoyl)-2-hydroxy-sn-glycero-3-[phospho-L-serine] (sodium salt), powder

Synonym(s):

110724

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About This Item

Empirical Formula (Hill Notation):
C23H43NNaO9P
CAS Number:
1246298-15-6
Molecular Weight:
531.55
UNSPSC Code:
51191904
NACRES:
NA.25

assay

99% (LPS; may contain up to 15% of the 2-LPS isomer, TLC)

form

powder

packaging

pkg of 1 × 100 mg (858141P-100mg)
pkg of 1 × 5 mg (858141P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 858141P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O.[Na+]

InChI

1S/C23H44NO9P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22(26)31-17-20(25)18-32-34(29,30)33-19-21(24)23(27)28;/h7-8,20-21,25H,2-6,9-19,24H2,1H3,(H,27,28)(H,29,30);/q;+1/p-1/b8-7-;/t20-,21+;/m1./s1

InChI key

OALJMCAGNYARLY-XZEOLHCOSA-M

Application

17:1 Lyso PS may be used as a standard in graphitized carbon black-solid phase extraction (GCB-SPE) method for lipid extraction.[1] It may also be used as an internal standard in the metabolomic analysis of cell and brain samples.[2]

Biochem/physiol Actions

17:1 Lyso PS may act as an odd-chained LIPIDOMIX™quantitative mass spectrometry internal standard.

Packaging

5 mL Clear Glass Sealed Ampule (858141P-100mg)
5 mL Clear Glass Sealed Ampule (858141P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Daisuke Ogasawara et al.
Nature chemical biology, 14(12), 1099-1108 (2018-11-14)
ABHD12 metabolizes bioactive lysophospholipids, including lysophosphatidylserine (lyso-PS). Deleterious mutations in human ABHD12 cause the neurological disease PHARC, and ABHD12-/- mice display PHARC-like phenotypes, including hearing loss, along with elevated brain lyso-PS and features of stimulated innate immune cell function. Here
Michela Antonelli et al.
Analytical and bioanalytical chemistry, 412(2), 413-423 (2019-11-25)
The chemical composition of Cannabis sativa L. has been extensively investigated for several years; nevertheless, a detailed lipidome characterization is completely lacking in the literature. To achieve this goal, an extraction and enrichment procedure was developed for the characterization of
Biyu Hou et al.
Life sciences, 245, 117352-117352 (2020-02-02)
The depot-specific differences in lipidome of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) reflect heterogeneity of white adipose tissue (WAT), which plays a central role in its distinct response to outside stimuli. However, the detailed lipidome of depot-specific
Jordon M Inloes et al.
Biochemistry, 57(39), 5759-5767 (2018-09-18)
Deleterious mutations in the serine hydrolase DDHD domain containing 1 (DDHD1) cause the SPG28 subtype of the neurological disease hereditary spastic paraplegia (HSP), which is characterized by axonal neuropathy and gait impairments. DDHD1 has been shown to display PLA1-type phospholipase

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