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810162C

Avanti

14:0-12:0 NBD PG

Avanti Research™ - A Croda Brand 810162C

Synonym(s):

1-myristoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-[phospho-rac-(1-glycerol)] (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C38H68N5O13P
CAS Number:
384833-03-8
Molecular Weight:
833.95
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810162C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810162C

concentration

1 mg/mL (810162C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

NBD PG is a lipid fluorescent probe with 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) attached to phosphatidylglycerol (PG). PG is localized to alveoli and is mostly found in the pulmonary surfactant.

Biochem/physiol Actions

7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) labeled fluorescence probes efficiently contributes to study the formation of membranes, micelles and reverse micelles. 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) phosphatidylglycerol (PG) serves as a substrate for enzyme assays. PG plays a vital role in the regulation of innate immune response and contributes to alveolar stability.

Packaging

5 mL Amber Glass Screw Cap Vial (810162C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Certificates of Analysis (COA)

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Marianna Agassandian et al.
Biochimica et biophysica acta, 1831(3), 612-625 (2012-10-03)
Pulmonary surfactant is essential for life and is composed of a complex lipoprotein-like mixture that lines the inner surface of the lung to prevent alveolar collapse at the end of expiration. The molecular composition of surfactant depends on highly integrated
H Raghuraman et al.
Biochimica et biophysica acta, 1768(5), 1258-1267 (2007-03-17)
Lipids that are labeled with the NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) group are widely used as fluorescent analogues of native lipids in biological and model membranes to monitor a variety of processes. The NBD group of acyl chain labeled NBD lipids is known
Maria Karatsa-Dodgson et al.
Journal of bacteriology, 192(20), 5341-5349 (2010-08-17)
Lipoteichoic acid (LTA) is an important cell wall component of Gram-positive bacteria. The key enzyme responsible for polyglycerolphosphate lipoteichoic acid synthesis in the Gram-positive pathogen Staphylococcus aureus is the membrane-embedded lipoteichoic acid synthase enzyme, LtaS. It is presumed that LtaS

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