W700544

Acesulfame potassium

≥99%, FG

• Synonym(s): Acesulfame K, 6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide potassium salt
• Empirical Formula (Hill Notation): C₄H₄KNO₄S
• CAS Number: 55589-62-3
• Molecular Weight: 201.24
• Beilstein/REAXYS Number: 3637857
• MDL number: MFCD00043833
• UNSPSC Code: 12352205
• E Number: E 950
• NACRES: NA.21

Properties

• grade: FG; Halal; Kosher
• Quality Level: 400
• reg. compliance: EU Regulation 1333/2008 & 178/2002; FDA 21 CFR 117
• assay: ≥99%
• application(s): flavors and fragrances
• documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• organoleptic: odorless
• SMILES string: [K+].CC1=CC(=O)[N-]S(=O)(=O)O1
• InChI: 1S/C4H5NO4S.K/c1-3-2-4(6)5-10(7,8)9-3;/h2H,1H3,(H,5,6);/q;+1/p-1
• InChI key: WBZFUFAFFUEMEI-UHFFFAOYSA-M

Description

Application

• Acesulfame potassium upregulates PD-L1 in HCC cells by attenuating autophagic degradation.: This study reveals that acesulfame potassium can upregulate PD-L1 expression in hepatocellular carcinoma cells by reducing autophagic degradation, which could have implications for cancer immunotherapy (Kim et al., 2024).


• Sweet taste receptors play roles in artificial sweetener-induced enhanced urine output in mice.: This study explores the role of sweet taste receptors in mediating the increased urine output observed with the consumption of artificial sweeteners like acesulfame potassium in mice (Cai et al., 2024).


• Molecular docking study of frequently used food additives for selected targets depending on the chromosomal abnormalities they cause.: A molecular docking study that examines the interaction of common food additives, including acesulfame potassium, with specific molecular targets associated with chromosomal abnormalities (Okus et al., 2024).


• Simultaneous analysis of natural and artificial sweeteners in sugar-free drinks and urine samples by column-switching UHPLC-charged aerosol detection method.: This paper presents a novel method for the simultaneous analysis of natural and artificial sweeteners, including acesulfame potassium, in sugar-free beverages and urine samples, enhancing analytical capabilities in food safety and health studies (Cheng et al., 2024).

Other Notes

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Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1