N17734

6-Nitroindoline

97%

• Synonym(s): 6-Nitro-2,3-dihydroindole, NSC 80658
• Empirical Formula (Hill Notation): C₈H₈N₂O₂
• CAS Number: 19727-83-4
• Molecular Weight: 164.16
• EC Number: 243-257-6
• MDL number: MFCD00005710
• UNSPSC Code: 12352100
• PubChem Substance ID: 24897527
• NACRES: NA.22

Properties

• assay: 97%
• form: powder
• mp: 67-69 °C (lit.)
• SMILES string: [O-][N+](=O)c1ccc2CCNc2c1
• InChI: 1S/C8H8N2O2/c11-10(12)7-2-1-6-3-4-9-8(6)5-7/h1-2,5,9H,3-4H2
• InChI key: LTNYDSMDSLOMSM-UHFFFAOYSA-N

Description

Application

• Reactant for preparation of 2-[(2,3-Dihydro-1H-indol-1-yl)methyl]melatonin analogs as novel MT2-selective melatonin receptor antagonists
• Reactant for synthesis of isoindigo and azaisoindigo glycosides as anticancer agents
• Reactant for preparation of arylfurancarboxamides with Nav1.8 voltage-gated Na channel blocking/analgesic activities
• Reactant for preparation of bicyclic benzamides as 5-HT1 receptor agonists
• Reactant for preparation of antiarrhythmic benzopyrans
• Reactant for preparation of 5-HT2C/2B receptor antagonists

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves