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F5396

Sigma-Aldrich

Fenbendazole

≥98%

Synonym(s):

Methyl 5-(phenylthio)-2-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C15H13N3O2S
CAS Number:
43210-67-9
Molecular Weight:
299.35
Beilstein/REAXYS Number:
759077
EC Number:
256-145-7
MDL number:
MFCD00144301
UNSPSC Code:
12352100
PubChem Substance ID:
57654186
NACRES:
NA.22

assay

≥98%

SMILES string

COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1

InChI

1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

InChI key

HDDSHPAODJUKPD-UHFFFAOYSA-N

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General description

Fenbendazole also known as Methyl 5-(phenylthio)-2-benzimidazolecarbamate, is a benzimidazole anthelmintic and antiprotozoal agent.

Application


  • Fenbendazole in Veterinary Medicine: Investigated for efficacy against coccidicidal fungi in avian species, demonstrating broad-spectrum antiparasitic potential. Additionally, its environmental impact and pharmacokinetics reveal insights for sustainable agricultural practices and disease vector control. (Lozano et al., 2024), (Hachgenei et al., 2024), (Durden et al., 2023).

  • Food safety and allergen detection: Fenbendazole′s implications in food safety are explored through quantitative PCR methods for detecting allergenic species in foods, underscoring the importance of accurate detection techniques in food industry compliance and safety standards (Costa et al., 2023).

  • Analysis of antibiotic and anthelmintic residues: The occurrence and exposure evaluation of Fenbendazole residues in cow milk in China is studied, emphasizing the need for rigorous monitoring of food products to ensure public health safety (Chang et al., 2023).


pictograms

Health hazardEnvironment
GHS08,GHS09

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2

target_organs

Liver,lymph node,Stomach,Nervous system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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A C Clark et al.
The Journal of small animal practice, 54(2), 99-103 (2012-11-14)
A 4-year-old, spayed-female great Dane was referred for surgical treatment of a suspected meningioma, diagnosed on magnetic resonance imaging 10 days prior to presentation. The suspected meningioma was removed via image-guided stereotactic craniotomy. Histopathological diagnosis was severe, locally extensive, chronic meningoencephalitis
Aileen Adam et al.
Veterinary parasitology, 177(3-4), 383-386 (2011-01-18)
On red grouse estates in the UK the nematode parasite Trichostrongylus tenuis is often controlled by application of grit medicated with the anthelmintic fenbendazole (FBZ). To date, assessment of the efficacy has been inhibited by the inability to quantify uptake
Walter Boyce et al.
Veterinary parasitology, 180(3-4), 256-261 (2011-04-19)
Canine peritoneal larval cestodiasis (CPLC) is a poorly understood disease of dogs caused by asexual multiplication of larval Mesocestoides spp. tapeworms. In this study, we examined the descriptive statistics and survival characteristics of 60 dogs diagnosed with CPLC from 1989
Moreno Rossi et al.
Journal of feline medicine and surgery, 13(10), 793-795 (2011-08-13)
An 8-month-old owned European cat showing abdominal pain, fever, distended painful bladder and urinary blockage was presented. Intravenous fluids were immediately administered and, after sedation, a urinary catheter was applied. Blood and urine analysis revealed cystitis and a moderate-to-severe degree
Niels C Kyvsgaard et al.
Veterinary parasitology, 181(2-4), 248-254 (2011-05-17)
Horses, mules and donkeys are indispensable farming and working animals in many developing countries, and their health status is important to the farmers. Strongyle parasites are ubiquitous in grazing horses world-wide and are known to constitute a threat to equine
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