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E8260

Sigma-Aldrich

Ethoxyquin

≥75% (capillary GC)

Synonym(s):

1,2-Dihydro-6-ethoxy-2,2,4-trimethylquinoline, 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline

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About This Item

Empirical Formula (Hill Notation):
C14H19NO
CAS Number:
Molecular Weight:
217.31
Beilstein/REAXYS Number:
158223
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

≥75% (capillary GC)

form

liquid

density

1.03 g/mL at 20 °C (lit.)

SMILES string

CCOc1ccc2NC(C)(C)C=C(C)c2c1

InChI

1S/C14H19NO/c1-5-16-11-6-7-13-12(8-11)10(2)9-14(3,4)15-13/h6-9,15H,5H2,1-4H3

InChI key

DECIPOUIJURFOJ-UHFFFAOYSA-N

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

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Victoria J Berdikova Bohne et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46(5), 1834-1843 (2008-03-11)
The biological fate of the fish feed additive, ethoxyquin (EQ) was examined in the muscle of Atlantic salmon during 12 weeks of feeding followed by a 2 weeks depuration period. Parent EQ (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline), quinone imine (2,6-dihydro-2,2,4-trimethyl-6-quinolone), de-ethylated EQ (6-hydroxy-2,2,4-trimethyl-1,2-dihydroquinoline) and
R Ørnsrud et al.
Journal of food protection, 74(9), 1574-1580 (2011-09-10)
The feed additive ethoxyquin (EQ) is a commonly used synthetic antioxidant preservative in animal feeds. In farmed Atlantic salmon fillets, EQ residues are present, both as the parent compound and as EQ derivatives. One of the main EQ derivates in
Ronald A Lubet et al.
Chemico-biological interactions, 182(1), 22-28 (2009-08-22)
Identifying agents that block tumor initiation is a goal of cancer prevention. The ability of a chemically varied group of agents to induce various drug metabolizing genes in livers of rats was examined. Sprague-Dawley rats were treated for 7 days
Toru Nishinaka et al.
Chemico-biological interactions, 191(1-3), 185-191 (2011-02-01)
Aldo-keto reductase 1B10 (AKR1B10) is an aldose reductase-like oxidoreductase of human origin. The expression of AKR1B10 is highly induced in the cells of various cancers such as lung non-small-cell carcinoma and hepatocellular carcinoma. Since the enzyme exhibits broad substrate specificities
Victoria J Berdikova Bohne et al.
Toxicological sciences : an official journal of the Society of Toxicology, 93(1), 11-21 (2006-06-23)
The synthetic antioxidant ethoxyquin (EQ) is increasingly used in animal feeds and has been candidate for carcinogenicity testing. EQ has the potential for toxicological and adverse health effects for both fish and fish consumers through "carryover" processes. The toxicological aspects

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