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ALD00034

Sigma-Aldrich

(S)-tert-Butyl 1-(chloromethyl)-5-hydroxy-1H-benzo[e]indole-3(2H)-carboxylate

95% (HPLC)

Synonym(s):

N-Boc-seco-CBI

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$99.62

About This Item

Empirical Formula (Hill Notation):
C18H20ClNO3
CAS Number:
Molecular Weight:
333.81
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22

$99.62

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Available to ship onApril 14, 2025Details


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assay

95% (HPLC)

form

powder

optical activity

[α]/D -89.0, c = 0.05% in chloroform

storage temp.

−20°C

SMILES string

OC1=C2C(C=CC=C2)=C3C(N(C(OC(C)(C)C)=O)C[C@H]3CCl)=C1

InChI

1S/C18H20ClNO3/c1-18(2,3)23-17(22)20-10-11(9-19)16-13-7-5-4-6-12(13)15(21)8-14(16)20/h4-8,11,21H,9-10H2,1-3H3/t11-/m1/s1

InChI key

DGPQGWRHSMFTSW-LLVKDONJSA-N

Application

N-Boc-CBI best used as its seco precursor (seco-N-Boc-CBI) is a simple alkylation subunit analog of that found in the naturally occurring antitumor agents the duocarmycins, yatakemycin, and CC-1065, which act by sequence selective DNA alkylation.

pictograms

Exclamation markEnvironment

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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