Skip to Content
MilliporeSigma
All Photos(1)

Documents

928925

Sigma-Aldrich

Poly(ethylene glycol)-block-poly(2-(Dimethylamino)ethyl methacrylate)

quaternized, PEG average Mn 5,000, quaternized PDMAEMA Mn 18,000

Synonym(s):

PEG-PQDMAEMA, Quaternized PEG-PDMAEMA

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3(C2H4O)nC6H7O2N(C9H18O2NCl)mC7H5S2
UNSPSC Code:
51171641
NACRES:
NA.25

Quality Level

100

form

powder

mol wt

PEG average Mn 5,000

color

white to pink

General description

Poly(ethylene glycol)-block-Poly(2-(Dimethylamino)ethyl methacrylate) quaternized (PEG-b-PQDMAEMA) is a biocompatible block polyelectrolyte composed of a neutral PEG block and a cationic quaternized Poly(2-(Dimethylamino)ethyl methacrylate) (PDMAEMA) block. The PQDMAEMA carries quaternary ammonium salt moieties along the polymer chain.

Application

  • Antimicrobial applications
  • Non-viral gene delivery

    PEG-b-PQDMAEMA is a versatile polymer with applications in antimicrobial applications and gene delivery. Due to its high efficacy in antimicrobial systems, it is an ideal candidate for the fabrication of long-lasting, contact-active bactericidal materials. PQDMAEMA is also a promising material for non-viral gene delivery. PEGylation of PQDMAEMA reduces cytotoxicity and increases gene delivery efficiency.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Quaternized poly(2-(dimethylamino)ethyl methacrylate)-grafted agarose copolymers for multipurpose antibacterial applications
Xu LQ, et al.
Royal Society of Chemistry Advances, 5, 61742-61742 (2015)
Film Properties and Antimicrobial Efficacy of Quaternized PDMAEMA Brushes: Short vs Long Alkyl Chain Length
Koufakis E, et al.
Langmuir, 36, 3482-3482 (2020)
PDMAEMA based gene delivery materials
Agarwal S, et al
Materials Today, 15, 388-388 (2012)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service