Azide functionalized gold nanoparticles are suitable for covalent conjugation of any molecule with a terminal alkyne through click chemistry. These gold nanoparticles allow for rapid generation of gold conjugates for subsequent use in downstream assays.
Azide functionalized gold nanoparticles are more than 95% spherical and have uniform size distribution (CV <12%).
Application
Ideal for development of gold conjugates for use in applications such as blotting, lateral flow assays, microscopy, and transmission electron microscopy (TEM).
Storage and Stability
When stored for a long period of time gold nanoparticles may sediment at the bottom of the vial, which is especially prominent for larger particle sizes. Prior to use, re-suspend the sedimented particles by thorough mixing until a homogenous solution is obtained.
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Glycoscience, despite its myriad of challenges, promises to unravel the causes of, potential new detection methods for, and novel therapeutic strategies against, many disease states. In the last two decades, glyco-gold nanoparticles have emerged as one of several potential new
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We present a new type of azide-functionalized gold nanoparticle and their coupling to an alkyne-modified DNA duplex using the copper(I)-catalyzed Huisgen cycloaddition ('click chemistry'), resulting in a chain-like assembly of nanoparticles on the DNA template.
Explore DNA-functionalized nanoparticles in sensors for precise target analyte detection. Learn about types, synthesis, functionalization, and design optimization, with insights into challenges and prospects.
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