911291
Polyester bis-MPA dendron 8 carboxyl, 1 biotin (core)
generation 3
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description
8 carboxyl, 1 biotin (core)
form
solid
mol wt
generation 3
no. Surface Groups
8
color
colorless to white
functional group
biotin (core)
storage temp.
−20°C
General description
- Polymer architecture: Dendron
- End Group Functionality: Carboxylic acid
- Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid
Application
Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allows their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers are biocompatible and biodegradable, making them suitable for biomedical applications. The carboxylic acid-functionalized corona and biotin-functionalized core of this product can be readily used in bioconjugation reactions.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.
Progress in Polymer Science, 48, 85-110 (2015)
Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.
Progress in Polymer Science, 48, 85-110 (2015)
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been
Articles
Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.
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