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705594

Sigma-Aldrich

Cortisol-9,11,12,12-d4

≥98 atom % D, ≥98% (CP)

Synonym(s):

11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-D4, 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-d4 (9,11,12,12-d4), 17-Hydroxycorticosterone-9,11,12,12-d4, 17-Hydroxycorticosterone-D4, 4-Pregnene-11β,17α,21-triol-3,20-dione-D4, 4-Pregnene-11β,17α,21-triol-3,20-dione-d4 (9,11,12,12-d4), Deuterated cortisol, Deuterated hydrocortisone, Hydrocortisone-9,11,12,12-d4, Kendall′s compound F (9,11,12,12-d4), Reichstein′s substance M (9,11,12,12-d4)

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5 MG
$962.00
10 MG
$336.00

$962.00

Estimated to ship onApril 12, 2025

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5 MG
$962.00
10 MG
$336.00

About This Item

Empirical Formula (Hill Notation):
C21D4H26O5
CAS Number:
73565-87-4
Molecular Weight:
366.48
MDL number:
MFCD10567120
UNSPSC Code:
41116107
PubChem Substance ID:
329762571
NACRES:
NA.24

$962.00

Estimated to ship onApril 12, 2025

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isotopic purity

≥98 atom % D

Quality Level

200

assay

≥98% (CP)

form

powder

technique(s)

mass spectrometry (MS): suitable

mp

211-214 °C

mass shift

M+4

storage temp.

−20°C

SMILES string

[2H]C1([2H])[C@]([2H])(O)[C@@]2([2H])[C@@H](CCC3=CC(=O)CC[C@]23C)[C@@H]4CCC(O)(C(=O)CO)[C@@]14C

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1/i10D2,16D,18D

InChI key

JYGXADMDTFJGBT-BJJKTIQHSA-N

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Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H361

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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MBBD7362
MBBD3455
MBBD4486
MBBD3178
MBBD2543

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Chen Li et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1061-1062, 163-168 (2017-07-25)
Cortisol and cortisone are two important glucocorticoids in human body, their interconversion is controlled by two isotypes of 11β-hydroxy steroid dehydrogenase (11β-HSD1 and 11β-HSD2). The ratio of urinary cortisol to cortisone can be used to assess the activity of 11β-HSDs.
Sergi Coll et al.
Drug testing and analysis, 11(11-12), 1589-1600 (2019-05-16)
Triamcinolone hexacetonide (THA) is a synthetic glucocorticoid (GC) used by intra-articular (IA) administration. GCs are prohibited in sports competitions by systemic routes, and they are allowed by other routes considered of local action (IA administration, among others). The aim of
Susanna Kortesluoma et al.
Psychoneuroendocrinology, 124, 105064-105064 (2020-12-02)
Previous research suggests that maternal prenatal psychological distress (PPD) is related to altered cortisol reactivity in the exposed child. There are indications for the sex differences in vulnerability for prenatal adversities that depend on the exposure and child outcome. Still
Sergi Coll et al.
Drug testing and analysis, 13(2), 348-359 (2020-09-20)
Betamethasone (BET) is prohibited in sports competitions when administered by systemic routes, and it is allowed by other routes for therapeutic purposes. In out-of-competition periods, there is no restriction of use. The present work aimed to assess the urinary excretion
Marloes L P Langelaan et al.
Endocrine connections, 7(4), 560-566 (2018-03-14)
Saliva as a diagnostic tool is patient friendly and offers analytical advantages. Hormonal analysis of saliva is not influenced by changes in concentrations of binding globulins as the free concentration of the hormones is measured. Analysis of salivary cortisol is
View All Related Papers

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