664006

Diethyl fluoro(phenylsulfonyl)methylphosphonate

97%

• Synonym(s): Diethyl [α-fluoro-α-(phenylsulfonyl)methyl]phosphonate, McCarthy′s reagent
• Empirical Formula (Hill Notation): C₁₁H₁₆FO₅PS
• CAS Number: 114968-97-7
• Molecular Weight: 310.28
• MDL number: MFCD08704785
• UNSPSC Code: 12352108
• PubChem Substance ID: 24884671

Properties

• assay: 97%
• reaction suitability: reaction type: C-C Bond Formation
• mp: 61-65 °C
• SMILES string: CCOP(=O)(OCC)C(F)S(=O)(=O)c1ccccc1
• InChI: 1S/C11H16FO5PS/c1-3-16-18(13,17-4-2)11(12)19(14,15)10-8-6-5-7-9-10/h5-9,11H,3-4H2,1-2H3
• InChI key: HUOWVYVTKZRXGM-UHFFFAOYSA-N

Description

Application

Reactant for:

• Radical-mediated thiodesulfonylation reactions
• Preparation of Bacillus subtilis S-ribosylhomocysteinase inhibitors
• Phenyl fluorovinyl sulfones via Julia olefination
• Horner-Wadsworth-Emmons reaction
• Negishi cross-coupling

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)